摘要
目的:探讨患者中性粒细胞/淋巴细胞比值(NLR)水平的变化,以期为院内心肺复苏(CPR)患者的预后提供新的预测指标。方法:选取2011—2018年间在我院急诊科经过CPR且自主循环恢复的244例住院患者,根据最终结局分为死亡组(n=204)和存活组(n=40),比较两组患者NLR水平的不同,绘制ROC曲线分析NLR对CPR患者预后的预测价值,并进行多因素Logistic回归分析。结果:死亡组患者NLR水平(21.4±18.8)明显高于存活组(11.2±9.4),组间比较差异有统计学意义(P<0.05)。绘制ROC曲线分析NLR与CPR患者预后的关系,结果发现,曲线下面积(AUC)为0.701,敏感度为82.89%,特异度为50%。Logistic回归分析:NLR水平上升(OR=1.062,95%CI:1.017~1.110)是影响CPR患者存活的独立危险因素。结论:在CPR患者中,患者的NLR值升高可提示患者预后质量较差,因此可根据血液中NLR来判断患者的预后质量,并对临床治疗提供指导。
Objective: To investigate the changes of neutrophil/lymphocyte ratio(NLR) levels in patients after in-hospital cardiopulmonary resuscitation, in order to provide new predictors for the prognosis of them. Method: A total of 244 inpatients who underwent cardiopulmonary resuscitation in the emergency department of our hospital from 2011 to 2018 were enrolled. They were divided into death group(n=204) and survival group(n=40) according to their final outcome. The differences in NLR levels between the two groups were compared. ROC curve was used to analyze the predictive value of NLR in the prognosis of patients after cardiopulmonary resuscitation, and multivariate logistic regression analysis was performed. Result: The NLR level(21.4±18.8) in the death group was significantly higher than that in the survival group(11.2±9.4). The difference between the two groups was statistically significant(P<0.05). ROC curve was used to analyze the relationship between NLR and the prognosis of patients after cardiopulmonary resuscitation. The results showed that the area under the curve(AUC) was 0.701, the sensitivity was 82.89%, and the specificity was 50%. Logistic regression analysis showed that increased NLR level(OR=1.062, 95%CI: 1.017-1.110) was an independent risk factor for prognosis of patients after cardiopulmonary resuscitation. Conclusion: In patients after cardiopulmonary resuscitation, elevated NLR values may indicate poor prognosis. So the NLR level can be used to evaluate the patient’s prognosis and guide clinical treatment.
作者
罗成准
王世伟
贾天元
王子达
陆晓晔
杨倩
朱长清
LUO Chengzhun;WANG Shiwei;JIA Tianyuan;WANG Zida;LU Xiaoye;YANG Qian;ZHU Changqing(Department of Emergency,Renji Hospital,School of Medicine,Shanghai JiaoTong University,Shanghai,200120,China)
出处
《临床急诊杂志》
CAS
2020年第2期143-146,共4页
Journal of Clinical Emergency
基金
国家自然科学基金面上项目(No:81671881).
关键词
心搏骤停
心肺复苏
中性粒细胞/淋巴细胞比值
预测
cardiac arrest
cardiopulmonary resuscitation
neutrophil/lymphocyte ratio
prediction
