摘要
目的:研究中医药治疗原发性胆汁性胆管炎(Primary Biliary Cholangitis,PBC)经验复方并分析其组方规律。方法:检索中国知网,将符合标准的中药治疗PBC经验文献中的药物进行分类,导入中医传承计算平台(V3.0),对处方中药物分类、使用频次、四气五味、药性归经进行演算并分析;同时运用R语言编程技术(V4.2.1)对高频药物进行聚类分析。结果:纳入文献69篇,挑选出中药复方137首,中药197味,药物分类频率较高的是补虚药,其次为活血化瘀药、利水渗湿药;性寒味苦类药居多,归经以肝经为主,脾经次之。聚类分析获得功效分别为益气健脾,活血化瘀,清热利湿等四个药物组方。结论:PBC临床表现复杂,但其临床治疗仍有一定规律可循。其治法与药物组方均以清热利湿,活血化瘀,益气健脾为主,以调和肝脾为主线贯穿全程。
Objective:To study the empirical compound of Traditional Chinese Medicine in the treatment of primary biliary cholangitis and analyze its formulation rules.Methods:The Chinese National Knowledge Infrastructure was searched to classify the drugs in the literature on the experience of TCM treatment of primary biliary cholangitis that met the inclusion and exclusion criteria,and imported into the Traditional Chinese Medicine Inheritance Computing platform(V3.0)to calculate and analyze the classification,frequency of use,four Qi(气),five flavor,and drug properties in the prescription.At the same time,R language programming technology(V4.2.1)was used for cluster analysis of high-frequency drugs.Results:Sixty-nine articles were included,and 137 TCM compounds were selected,with 197 TCM compounds.The drugs with the highest frequency of classification were tonifying deficiency,followed by drugs for promoting blood circulation and removing blood stasis,and drugs for improving water and dampness.Conclusion:The clinical manifestations of primary biliary cholangitis is complicated,but its clinical treatment law still exists.Its treatment and drug group are mainly clearing heat and benefiting dampness,promoting blood circulation and removing blood stasis,invigorating Qi and spleen,and harmonizing liver and spleen as the main line throughout the whole process.
出处
《中医临床研究》
2022年第35期42-46,共5页
Clinical Journal Of Chinese Medicine
关键词
中医传承计算平台
R语言
原发性胆汁性胆管炎
文献挖掘
用药规律
Traditional Chinese Medicine Inheritance Computing platform
R language
Primary biliary cholangitis
Literature mining
Low of medication
