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艾箱灸治疗阿帕替尼相关性腹泻的回顾性研究及临床体会

Retrospective study and clinical experience of box moxibustion in the treatment of Apatinib-associated diarrhea
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摘要 目的:探讨艾箱灸对于阿帕替尼相关性腹泻的治疗效果并总结临床治疗体会。方法:回顾收集广州中医药大学第二附属医院2018年1月-2019年5月收治使用阿帕替尼并产生相关性腹泻住院及门诊患者病历,将其分为常规治疗组及艾灸+常规治疗组,其中常规治疗组治疗包括口服止泻药物治疗,艾灸+常规治疗组在此基础上加用艾灸神阙穴,气海穴及关元穴三穴,记录治疗后两组腹泻情况变化。应用SPSS 19.0统计分析软件进行统计,分析探讨艾箱灸治疗阿帕替尼相关性腹泻的临床疗效以及优势,并总结阿帕替尼相关性腹泻的中医临床辨证体会。结果:艾灸+常规治疗组总有效率较常规治疗组总有效率高,且P<0.05,两者差异对比有统计学意义。结论:联合中医艾灸疗法对比单纯应用现代医学手段治疗阿帕替尼相关性腹泻效果更佳。 Objective:To investigate the therapeutic effect of box moxibustion on Apatinib-related diarrhea and to summarize the clinical experience.Methods:The medical records of patients receiving treatment of Apatinib and related diarrhea in Guangdong Hospital of Traditional Chinese Medicine from January 2018 to May 2019 were retrospectively collected.They were divided into the conventional treatment group and moxibustion+conventional treatment group.The treatment in the conventional treatment group included oral antidiarrheal medication.On this basis,moxibustion and conventional treatment group were added with moxibustion at Shenque(神阙)(RN08),Qihai(气海)(RN06)and Guanyuan(关元)(RN04)acupoints,and the changes of diarrhea in the two groups were recorded after treatment.SPSS 19.0 statistical analysis software was used to analyze and discuss the clinical efficacy and advantages of box moxibustion in the treatment of Apatinib-related diarrhea,and to summarize the experience of TCM clinical syndrome differentiation for Apatinib-related diarrhea.Results:The total effective rate of moxibustion+conventional treatment group was higher than that of the conventional treatment group,and P<0.05,the difference was statistically significant.Conclusion:Moxibustion combined with traditional Chinese medicine is more effective in the treatment of Apatinib-related diarrhea.
作者 邱芬梅 刘宇
出处 《中医临床研究》 2022年第24期76-78,共3页 Clinical Journal Of Chinese Medicine
关键词 阿帕替尼 腹泻 艾箱灸 回顾性分析 临床经验 Apatinib Diarrhea Moxa box moxibustion Retrospective analysis Clinical experience
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