摘要
目的:研究核桃分心木的化学成分。方法:采用硅胶、ODS等柱色谱结合HPLC技术对核桃分心木70%乙醇提取物进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。结果:从核桃分心木中分离得到6个化合物,分别鉴定为:juglandisde A(1)、salviaplebeiaside(2)、3′-O-β-D-glucopyranoside of 4-(3′,4′-dihydroxyphenyl)butan-2-one(3)、benzyl-β-D-glucopyranoside(4)、phenylethyl-β-D-glucopyranoside(5)和methyl(6-O-p-hydroxy-benzoyl)-β-D-glucopyranoside(6)。结论:其中,化合物1为新的苯基丁酮苷类化合物,化合物2和3为首次从核桃分心木中分离得到。
Objective:To study the chemical constituents of Juglans regia.Methods:The 70%ethanol extract of Juglans regia was isolated and purified through silica column,ODS column and HPLC.The structures of obtained compounds were identified by physicochemical properties and spectral data.Results:Six compounds were isolated from Juglans regia and identified as juglandisde A(1),salviaplebeiaside(2),3'-O-β-D-glucopyranoside of 4-(3',4'-dihydroxyphenyl)butan-2-one(3),benzyl-β-D-glucopyranoside(4),phenylethyl-β-D-glucopyranoside(5),methyl(6-O-p-hydroxy-benzoyl)-β-D-glucopyranoside(6),respectively.Conclusion:Among them,compound 1 is a new phenylbutanone glucoside,compounds 2 and 3 are isolated from Juglans regia for the first time.
作者
谭金燕
李建丽
程艳刚
乔元彪
李青山
王颖莉
TAN Jin-yan;LI Jian-li;CHENG Yan-gang;QIAO Yuan-biao;LI Qing-shan;WANG Ying-li(Shanxi University of Chinese Medicine,Shanxi Modern Chinese Medicine Engineering Laboratory,Jinzhong 030619,China;Shanxi University of Chinese Medicine,Shanxi Key Laboratory of Innovative Drug for the Treatment of Serious Diseases Basing on the Chronic Inflammation,Jinzhong 030619,China)
出处
《中药材》
CAS
北大核心
2022年第8期1857-1860,共4页
Journal of Chinese Medicinal Materials
基金
山西省卫生健康委员会科研项目(2020094)
基于炎性反应的重大疾病创新药物山西省重点实验室开放基金资助项目(2021sxcxyw10)
中央引导地方科技发展资金项目(YDZX20201400001518)
山西中医药大学科技创新能力培育计划项目(2021PY-JC-05,2021PY-JC-09)
关键词
核桃分心木
苯基丁酮苷
结构鉴定
Juglans regia L.
Phenylbutanone glucoside
Structure identification
