摘要
食管癌作为全球常见的消化道肿瘤疾病负担较重,严重威胁人民的生命健康。我国食管癌发病率和死亡率均占全球50%以上。焦虑、抑郁作为食管癌的常见共患病,是食管癌的独立危险因素,影响患者的生活质量和预后转归。该文就食管癌合并焦虑、抑郁的流行病学特点、可能原因和发生机制、筛查方法、影响因素和治疗等方面进行综述,发现食管癌合并焦虑、抑郁的患病率异质性较大,可能受筛查诊断工具、诊断标准、研究对象及样本量等因素影响。
Esophageal cancer,a common gastrointestinal cancer in the world,threatens people’s life and health seriously with heavy disease burden both for individuals and the society.The incidence and mortality of esophageal cancer in China account for more than 50%of the incidence and mortality in the world.Anxiety and depression,as one of the common comorbidities of esophageal cancer,are independent risk factors affecting the quality of life and prognosis of patients.The prevalence of anxiety and depression in esophageal cancer patients may be affected by screening tools,diagnostic criteria,patients’characteristics and sample size.This article reviews the epidemiological characteristics,the causation and mechanism,screening and diagnostic methods,influencing factors and treatments of anxiety and depression in esophageal cancer patients.
作者
朱娟
王少明
陈茹
李新庆
魏文强
ZHU Juan;WANG Shao-ming;CHEN Ru;LI Xin-qing;WEI Wen-qiang(National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)
出处
《中国肿瘤》
CAS
CSCD
北大核心
2020年第1期55-62,共8页
China Cancer
基金
国家重点研发计划精准医学研究(2016YFC0901400
2016YFC0901404)
协和青年科研基金(2017330004).
关键词
食管癌
焦虑
抑郁
esophageal cancer
anxiety
depression
