摘要
目的分析阿卡波糖联合格列吡嗪治疗2型糖尿病患者的临床疗效。方法将本院于2016年1月至2020年12月接收治疗的80例2型糖尿病患者作为本次研究对象,按照随机数字表法分为观察组和对照组,对比分析两组患者治疗后临床疗效、治疗前后空腹血糖、餐后血糖以及糖化血红蛋白水平、治疗后并发症发生率。结果两组患者之间临床疗效对比:观察组患者临床疗效90.0%,对照组患者临床疗效70.0%,相较于对照组患者,观察组患者更高,对比统计学差异(P<0.05);相较于对照组,观察组患者并发症发生率明显更低,对比统计学差异明显(P<0.05);治疗前,两组患者空腹血糖、餐后血糖以及糖化血红蛋白水平对比并无显著差异(P>0.05),治疗后,相较于对照组患者,观察组患者空腹血糖、餐后血糖以及糖化血红蛋白水平明显更低,对比统计学差异明显(P<0.05)。结论在2型糖尿病患者的临床治疗中针对患者采用阿卡波糖联合格列吡嗪治疗可明显提高患者临床疗效,降低血糖水平,稳定性良好,相较于单独用格列吡嗪治疗并发症发生率更低,具有较高的安全性,能够保证患者治疗安全,值得临床广泛应用。
Objective To analyze the clinical efficacy of acarbose combined with Glipizide in the treatment of type 2 diabetes mellitus.Methods Eighty patients with type 2 diabetes who were treated in our hospital from January 2016 to December 2020 were selected as the research objects and randomly divided into the observation group and the control group.The clinical efficacy,fasting blood glucose,postprandial blood glucose and glycosylated hemoglobin levels before and after treatment,and the incidence of complications after treatment of the two groups were compared and analyzed.Results Comparison of clinical efficacy between the two groups:The clinical curative effect of patients in the observation group is 90.0%,and the clinical curative effect of patients in the control group is 70.0%.Compared with the control group,the observation group has a higher clinical effect,and the comparison is statistically different(P<0.05).Compared with the control group,the incidence of complications in the observation group was significantly lower,the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in the levels of fasting blood glucose,postprandial blood glucose and glycosylated hemoglobin between the two groups(P>0.05).After treatment,the levels of fasting blood glucose,postprandial blood glucose and glycosylated hemoglobin in the observation group were significantly lower than those in the control group(P<0.05).Conclusion In the clinical treatment of patients with type 2 diabetes,acarbose combined with Glipizide treatment can significantly improve the clinical efficacy of patients,reduce the blood glucose level,good stability,compared with Glipizide treatment alone,the incidence of complications is lower,high safety,ensure safety of patient treatment,it is worthy of clinical wide application.
作者
陈东
付从江
CHEN Dong;FU Cong-jiang(Qitai Farm Branch of Qitai Hospital of the Sixth Division of Xinjiang Production and Construction Corps,Changji,Xinjiang 831809;Xinjiang Production and Construction Corps Sixth Division Hospital Military Farm Branch,Changji,Xinjiang 831111)
出处
《智慧健康》
2021年第31期99-101,共3页
Smart Healthcare
