摘要
目的探讨对于严重创伤且需要进行输血的患者,采取大量输血对其凝血功能的影响。方法选取我院2018年2月至2019年4月收治的81例严重创伤患者为研究对象,随机分成观察组(n=41)与对照组(n=40),对照组在创伤的抢救上给予输注小于本身血容量1倍的血液,而观察组则输注大于等于本身血容量1.5倍的血液,输注前与输注1d后对两组凝血功能与输血后6d内不良反应发生情况进行观察。结果在输血1d后,两组PT、APTT、TT与FIB指标水平均较输血前降低,但观察组降低幅度明显要比对照组更显著(P<0.05);输血后6d观察组不良反应总发生率为14.63%,显著高于对照组2.50%的总发生率(P<0.05)。结论对严重创伤的患者,给予大量输血可以有效纠正患者的凝血功能,但是在输血后需注意不良反应的预防,保证疾病治疗效果。
Objective To investigate effect of massive blood transfusion on coagulation function of patients with severe trauma needing blood transfusion.Methods We chose 81 cases of severe trauma patients admitted to our hospital from February 2018 to April 2019 as research objects,divided them into observation group(n=41)and control group(n=40)randomly.Control group was treated with infusion of blood less than 1 time of own blood volume for trauma rescue,while observation group with blood greater than or equal to 1.5 times of own blood volume.Observe coagulation function of two groups before and 1 day after transfusion and adverse reactions within 6 days after transfusion.Results 1 day after blood transfusion,levels of PT,APTT,TT and FIB in two groups were lower than before blood transfusion,reduction in observation group was significantly more significant than control group(P<0.05);6 days after blood transfusion,total adverse reactions incidence in observation group was 14.63%,significantly higher than 2.50%in control group(P<0.05).Conclusion Massive bleeding can correct coagulation function of severe trauma patients effectively,after blood transfusion,attention should be paid to prevent adverse reactions to ensure treatment effect of disease.
作者
崔会芬
CUI Hui-fen(Department of Blood Transfusion,The First People’s Hospital of Qujing,Qujing,Yunnan,655000)
出处
《智慧健康》
2020年第33期67-68,共2页
Smart Healthcare
关键词
大量输血
严重创伤
凝血功能
Massive blood transfusion
Severe trauma
Coagulation function
