摘要
目的探究硫酸沙丁胺醇联合常规治疗小儿喘息性疾病的临床效果和安全性。方法选取2017年1月至2018年11月期间我科收治的以喘息入院患儿,以随机数字表法随机分为研究组(40例)和参照组(39例)。参照组给予常规治疗,研究组在参照组的基础上予以硫酸沙丁胺醇治疗。两组患者均治疗6天后观察其平均住院天数、喘息缓解时间、肺部啰音消失时间、嗜酸性粒细胞、总有效率及不良反应发生情况。结果研究组平均住院天数、喘息缓解时间以及肺部啰音消失时间均短于参照组(P<0.05);治疗后研究组的嗜酸粒细胞较低于参照组(P<0.05);研究组的近期临床治疗的总有效率较高于参照组(P<0.05);研究组的不良反应发生率相比于参照组无明显差异(P>0.05)。结论硫酸沙丁胺醇联合常规治疗小儿喘息性疾病较安全且效率较高,可作为临床上的参考。
Objective To explore the clinical effect and safety of salbutamol sulfate combined with conventional treatment for children with asthmatic diseases.Methods From January 2017 to November 2018,children admitted to our department with wheezing were randomly divided into study group(40 cases)and reference group(39 cases)by random number table method.The reference group was given conventional treatment,and the study group was given salbutamol sulfate treatment on the basis of the reference group.The average hospitalization days,wheezing relief time,disappearance time of lung rales,eosinophils,total effective rate and adverse reactions were observed after 6 days of treatment in both groups.Results The average hospitalization days,wheezing relief time and disappearance time of lung rales in the study group were shorter than those in the reference group(P<0.05).The eosinophils in the study group were lower than those in the reference group after treatment(P<0.05),the total effective rate of recent clinical treatment in the study group was higher than that in the reference group(P<0.05),the incidence of adverse reactions in the study group was not significantly different from that in the reference group(P>0.05).Conclusion Salbutamol sulfate combined with conventional treatment is safe and effective in children with asthmatic diseases,which can be used as a clinical reference.
作者
黄本羡
HUANG Ben-xian(Pediatrics,Guzhen People’s Hospital,Zhongshan,Guangdong 528421)
出处
《智慧健康》
2020年第32期103-105,共3页
Smart Healthcare
关键词
小儿喘息
沙丁胺醇
疗效
安全性
Pediatric wheezing
Salbutamol
Efficacy
Safety
