摘要
目的探讨地中海贫血筛查在产前检查中的应用研究。方法对我院2016年1月至2020年1月入院接受孕前产检的孕妇进行地中海贫血筛查,纳入100例疑似地中海贫血孕妇设为研究组;纳入100例正常健康孕妇设为对照组。所有孕妇均接受地中海贫血筛查,观察对比筛查准确率。结果研究组100例孕妇中,基因筛查准确率为100.00%、血红蛋白电泳筛查准确率为89.00%、血常规测定法筛查准确率为87.00%;研究组孕妇的平均红细胞体积(88.82±3.91)fl高于对照组(65.81±4.91)fl,血红蛋白(20.48±4.91)pg低于对照组(30.83±2.84)pg,有统计学意义(P<0.05)。结论在孕妇产前检查中进行地中海贫血筛查,能够有效的避免地中海贫血患儿的出生,提升优生优育率,减轻社会负担,产前检查中增加地中海贫血的筛查十分必要。
Objective To investigate the application of thalassemia screening in prenatal examination.Methods Screening of thalassemia was conducted on pregnant women who were admitted to our hospital for pre-pregnancy examination from January 2016 to January 2020,and 100 cases of pregnant women suspected of thalassemia were included into the research group.100 healthy pregnant women were included as the control group.All pregnant women were screened for thalassemia.Results Among the 100 pregnant women in the study group,the accuracy of gene screening was 100.00%,the accuracy of hemoglobin electrophoresis was 89.00%,and the accuracy of blood routine assay was 87.00%.The mean erythrocyte volume(88.82±3.91)fl of pregnant women in the study group was higher than that of the control group(65.81±4.91)fl,and the hemoglobin(20.48±4.91)pg was lower than that of the control group(30.83±2.84)pg,showing statistical significance(P<0.05).Conclusion Screening for thalassemia in the prenatal examination of pregnant women can effectively avoid the birth of children with thalassemia,improve the rate of good birth and good childbirth,and reduce the social burden.It is necessary to increase the screening for thalassemia in the prenatal examination.
作者
蔡惠
CAI Hui(Perinatal health care department,maternal and child health planning service center,Huidong county,Huizhou,Guangdong 516300)
出处
《智慧健康》
2020年第19期14-15,18,共3页
Smart Healthcare
关键词
地中海贫血
产前筛查
产前检查
基因诊断
筛查效果
Thalassemia
Prenatal screening
Prenatal testing
Genetic diagnosis
Effect of screening
