摘要
目的分析2013-2020年福建省泉州市食源性疾病病例监测中所检出的沙门氏菌血清型,并分析耐药性。方法选择2013-2020年福建省泉州市食源性疾病监测哨点医院采集的从腹泻患者生物标本中分离的沙门氏菌株115株,采用玻片凝集方法进行沙门氏菌血清型鉴定,采用微量肉汤稀释法进行药敏试验。结果血清型鉴定表明分属于5个血清群,包括B群(73.04%)、C1群(3.48%)、C2群(4.35%)、D群(15.65%)及E1群(2.61%);包含24种血清型,以B群血清型检出最多(9种,占37.50%),其中主要血清型为圣保罗沙门氏菌(27.83%)、鼠伤寒沙门氏菌(26.09%)以及阿雷查瓦莱塔沙门氏菌(9.57%)。分离的菌株对12种抗生素产生耐药,其中对头孢唑林、阿米卡星、庆大霉素、妥布霉素4种抗生素全部耐药。结论2013-2020年福建省泉州市食源性疾病监测哨点分离的沙门氏菌血清型分布呈多态性,对多种抗生素产生较高的耐药性。
Objective To analyze the serotype and drug-resistance of Salmonellaisolated from patients with foodborne diseases in Quanzhou city from 2013to 2020.Methods A total of 115 Salmonellastrains were isolated from patients with infectious diarrhea collected from the sentinel hospital of foodborne disease surveillance in Quanzhou city,the serotype of Salmonella was identified by slide agglutination and micro broth dilution method was used for the analysis of drugresistance.Results Serotyping revealed 5serogroups including group B(73.04%),C1(3.48%),C2(4.35%),D(15.65%),and E1(2.61%);containing 24serotypes,with the highest number of serotypes in group B(9serotypes,37.50%),of which the major serotypes were Salmonella saintpaul(27.83%),Salmonella typhimurium(26.09%)and Salmonella arechavaleta(9.57%).Analysis of the drug-resistance showed that all the isolated strains were resistant to 12 kinds of antibiotics,including cefzolin,amikacin,gentamicin and tobramycin.Conclusion Clinical isolates of Salmonella from patients with infectious diarrhea in Quanzhou city from 2013to 2020are resistant to multiple antibiotics,and the serotype distribution is polymorphic.
作者
刘建忠
叶聿程
陈韵妍
吴小凤
郑友限
LIU Jian-zhong;YE Yu-cheng;CHEN Yun-yan;WU Xiao-feng;ZHENG You-xian(Microbiological laboratory,Quanzhou City Center for Disease Control and Prevention,Fujian 362000,China;Clinical laboratory,Anxi County Center for Disease Control and Prevention)
出处
《预防医学论坛》
2023年第12期915-918,共4页
Preventive Medicine Tribune
基金
福建省泉州市科技计划项目课题(2020N067S)
关键词
食源性疾病
沙门氏菌
血清型
耐药
Foodborne diseases
Salmonella
Serotype
Drug-resistance
