摘要
目的:观察在实施超声下引流术治疗的基础上,对肝脓肿患者联合实施柴胡清肝汤治疗的临床效果。方法:选取三明市第一医院2021年2月至2022年3月期间收治的64例肝脓肿患者,采用盲选抽签法分为对照组与观察组,各32例。对照组患者给予超声下引流术,观察组患者在对照组的基础上给予柴胡清肝汤治疗,观察和比较两组患者的治疗效果、临床相关指标、治疗前后肝功能指标、炎症因子水平、并发症发生率。结果:观察组患者治疗总有效率为96.88%,高于对照组的78.13%,差异具有统计学意义(P<0.05)。观察组患者体温恢复时间、拔管时间、脓肿消失时间、住院时间均短于对照组,差异具有统计学意义(P<0.05)。治疗后观察组患者谷草转氨酶(AST)、谷丙转氨酶(ALT)水平均低于对照组,差异具有统计学意义(P<0.05)。治疗后观察组患者血清C反应蛋白(CRP)、白细胞介素-6(IL-6)、降钙素原(PCT)、肿瘤坏死因子-α(TNF-α)水平均低于对照组,差异具有统计学意义(P<0.05)。观察组患者的并发症发生率为6.25%,低于对照组的18.75%,差异具有统计学意义(P<0.05)。结论:在实施超声下引流术治疗的同时,对肝脓肿患者联合柴胡清肝汤治疗的效果更为确切,可降低炎症因子水平,改善患者肝功能,且并发症少,有较高安全性。
Objective To observe the clinical effect of ultrasound-guided drainage combined with Chaihu Qinggan decoction in the treatment of liver abscess.Methods A total of 64 patients with liver abscess admitted to Sanming First Hospital from February 2021 to March 2022 were selected and divided into a control group and an bservation group by blind selection lottery method,with 32 cases in each group.The patients in the control group were treated with ultrasound-guided drainage,and the patients in the observation group were treated with Chaihu Qinggan decoction on the basis of the control group.The therapeutic effect,clinical related indicators,liver function indicators before and after treatment,inflammatory factor levels,and the incidence of complications were observed and compared between the two groups.Results The total effective rate of the observation group was 96.88%,higher than 78.13%of the control group,and the difference was statistically significant(P<0.05).The body temperature recovery time,extubation time,abscess disappearance time and hospitalization time of the observation group were shorter than those of the control group,and the differences were statistically significant(P<0.05).After treatment,the leves of aspartate aminotransferase(AST)and alanine aminotransferase(ALT)of the observation group were lower than those of the control group,and the differences were statistically significant(P<0.05).After treatment,the leves of C-reactive protein(CRP),interleukin-6(IL-6),procalcitonin(PCT)and tumor necrosis factor-α(TNF-α)in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 6.25%,lower than 18.75%in the control group,and the difference was statistically significant(P<0.05).Conclusion Ultrasound-guided drainage combined with Chaihu Qinggan decoction is more effective in the treatment of liver abscess,which can reduce the level of inflammatory factors,improve the liver function of patients,and has few complications and high safety.
作者
章昱婷
邱建钊
邓小艳
ZHANG Yu-ting;QIU Jian-zhao;DENG Xiao-yan(Sanming First Hospital,Fujian Sanming 365000)
出处
《深圳中西医结合杂志》
2022年第20期34-37,共4页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词
肝脓肿
超声下引流术
柴胡清肝汤
Liver abscess
Ultrasound-guided drainage
Chaihu Qinggan decoction
