摘要
目的探讨结缔组织病相关肺动脉高压的临床特点以及临床意义。方法随机选定结缔组织病相关肺动脉高压患者51例(2018年1月—2019年12月期间)作为研究对象,并对51例结缔组织病相关肺动脉高压患者的临床特点进行分析。结果51例结缔组织病相关肺动脉高压患者的临床表现有:雷诺现象、心包积液、胸腔积液、多关节炎与肺间质病变;在血清免疫学指标中,51例结缔组织病相关肺动脉高压患者的C3指标会更低于非肺动脉高压患者,而CRP、CIC与ESR指标则均会更高于非肺动脉高压患者,差异有统计学意义(P<0.05)。结论雷诺现象、心包积液、胸腔积液、多关节炎、肺间质病变等临床表现与血清免疫学指标中的C3、CRP、CIC与ESR指标均能够作为早期诊断结缔组织肺动脉高压疾病的依据,并且,在临床治疗中需要依据患者实际临床表现进行防治,以便改善患者预后。
Objective To explore the clinical features and clinical significance of pulmonary hypertension associated with connective tissue disease.Methods 51 patients with connective tissue disease related pulmonary hypertension(from January 2018 to December 2019)were randomly selected as the research object,and the clinical characteristics of 51 patients with connective tissue disease related pulmonary hypertension were analyzed.Results The clinical manifestations of 51 patients with connective tissue disease-associated pulmonary hypertension were:Raynaud's phenomenon,pericardial effusion,pleural effusion,polyarthritis,and pulmonary interstitial lesions;of the serum immunological indicators,51 cases of connective tissue disease-associated pulmonary artery The C3 index of patients with hypertension will be lower than that of patients with non-pulmonary hypertension,while the CRP,CIC and ESR indicators will be higher than those of patients with non-pulmonary hypertension,with significant difference(P<0.05).Conclusion Raynaud's phenomenon,pericardial effusion,pleural effusion,polyarthritis,pulmonary interstitial lesions and other clinical manifestations and serum immunological indicators C3,CRP,CIC and ESR indicators can be used as early diagnosis of connective tissue pulmonary hypertension disease Basis,and in clinical treatment,it is necessary to prevent and treat according to the actual clinical manifestation of the patient in order to improve the patient's prognosis.
作者
周持恒
王钦清
ZHOU Chiheng;WANG Qinqing(Intensive Care Unit,Asian Heart Hospital,Wuhan 430000,China)
出处
《实用心脑肺血管病杂志》
2020年第S01期101-102,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
结缔组织病
肺动脉高压
临床特点
临床意义
Connective tissue disease
Pulmonary hypertension
Clinical characteristics
Clinical significance
