摘要
目的探究酒石酸美托洛尔、盐酸替罗非班注射液治疗急性心肌梗死的临床效果。方法将武警宁夏总队医院2016年11月—2019年6月接收的86例急性心肌梗死患者按照随机化原则分为两组,对照组(n=43)采用酒石酸美托洛尔治疗,治疗组(n=43)在对照组治疗基础上采用盐酸替罗非班注射液治疗。比较两组治疗效果、心功能指标和不良心血管事件发生率。结果对照组总疗效为81.40%,低于治疗组的95.35%,差异有统计学意义(χ~2=4.0737,P<0.05);两组治疗后心功能指标均得到改善,以治疗组改善的效果更加理想,差异有统计学意义(P<0.05);治疗组不良心血管事件发生率为4.65%,低于对照组的23.26%,差异有统计学意义(χ~2=6.1982,P<0.05)。结论盐酸替罗非班注射液和酒石酸美托洛尔联用于急性心肌梗死患者中效果确切,既能改善心功能,又可减少不良心血管事件,值得临床推广运用。
Objective To explore the clinical effect of metoprolol tartrate and tirofiban hydrochloride injection on acute myocardial infarction.Methods 86 patients with acute myocardial infarction received in the hospital from November 2016 to June 2019 were divided into two groups according to the principle of randomization.The control group(n=43)was treated with metoprolol tartrate and the treatment group(n=43)was treated with tirofiban hydrochloride injection on the basis of the control group.The therapeutic effect,cardiac function index and incidence of adverse cardiovascular events were compared between the two groups.Results The total curative effect of the control group was 81.40%,which was lower than 95.35%of the treatment group,with statistical significance(χ~2=4.0737,P<0.05);the cardiac function indexes of the two groups were improved after treatment,and the improvement effect of the treatment group was more ideal,with statistical value(P<0.05);the incidence of adverse cardiovascular events in the treatment group was 4.65%,which was lower than that in the control group(23.65%).26%,with significant difference(χ~2=6.1982,P<0.05).Conclusion Tirofiban hydrochloride injection combined with metoprolol tartrate in the treatment of acute myocardial infarction has a definite effect.It can not only improve cardiac function,but also reduce adverse cardiovascular events.It is worthy of clinical application.
作者
冯艳
张理华
谭宝强
FENG Yan;ZHANG Lihua;TAN Baoqiang(Department of Internal Medicine,Ningxia General Hospital of Yinchuan City,Yinchuan 750001,China;Emergency Department,Ningxia General Hospital of Yinchuan City,Yinchuan 750001,China)
出处
《实用心脑肺血管病杂志》
2019年第S02期89-90,共2页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
美托洛尔
急性心肌梗死
替罗非班注射液
不良心血管事件
Metoprolol
Acute myocardial infarction
Tirofiban injection
Adverse cardiovascular events
