摘要
激光诱导击穿光谱(Laser-induced Breakdown Spectroscopy,LIBS)技术是一种快速、多元素同时检测的微区分析技术。激光脉冲通过对样品表面的激光灼烧,获取样品组成元素的等离子体光谱,从而实现样品的分析。作为一种绿色的、高效的元素检测技术,LIBS具有样品制备简单、无损或微损等优势,能够实现多元化对象(包括固体、液体、气体、气溶胶四种形态的物质)的原位、在线及远程检测。随着LIBS技术日趋成熟及相关科学理论的发展,LIBS成为了中药行业的新兴分析检测工具。本文简述了LIBS的基本原理,综述了其在中药中的元素分析、产地鉴别、药材真伪掺假、重金属检测及生产过程控制的应用及进展。LIBS技术在中药测领域的应用具有很大潜力,必将成为中药质量评价重要手段。
Laser-induced breakdown spectroscopy(LIBS)is a fast qualitative and quantitative multi-element analytical technology,which uses a high power laser pulse to ablate a target and generate laser induced plasma.The emission line emitted from the plasma is used as a spectral characteristic for identifying the presence of characteristic elements in a sample.The spectroscopy provides information on elemental compositions,regardless its state of matter(solid,liquid,gas and aerosol).As a green elemental microanalysis,LIBS has merits of minimal sample preparation,no or little sample damage,in situ and even remote detection.Thus,it has been applied in several domains and confirmed its high utility in fast qualitative and quantitative analysis of diverse elements.With the gradual development of relevant scientific theories,it has become a promising analytical detection tool in traditional Chinese medicine(TCM).The article resumed the LIBS basic theory and reviewed the application and development of LIBS in element analysis,provenance discrimination,authenticity and adulteration,heavy mental detection and production process control of TCM.LIBS,a promising multi-element analytical technology,can become an important means of quality evaluation of TCM.
作者
刘晓娜
王喜波
车晓青
吴志生
李德芳
郑秋生
Liu Xiaona;Wang Xibo;Che Xiaoqing;Wu Zhisheng;Li Defang;Zheng Qiusheng(School of Integrated Traditional Chinese and Western Medicine,Binzhou Medical University,Yantai,264003,China;Penglai Municipal Bureau of Ocean Development and Fishery,Penglai 265600,China;Shandong Runzhong Pharmaceutical Co.,Ltd.,Yantai,264003,China;School of Chinese Materia Media,Beijing University of Traditional Chinese Medicine,Beijing,100102,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2020年第4期1262-1269,共8页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
国家自然科学基金青年科学基金项目(81903796):基于中药双向调节药效特异性的西洋参质量评价方法研究,主持人:刘晓娜
山东省高等学校科技计划项目(科技类)A(J18KA287):基于多元信息融合的阿胶质量标准评价方法研究,主持人:刘晓娜
滨州医学院科研启动基金(BY2016KYQD02):基于LIBS技术的安宫牛黄丸中砷和汞元素定量评价研究,主持人:刘晓娜
滨州医学院大学生创新创业训练计划项目(201810440142):基于四时五味养生观的中药茶剂研究,主持人:李佩窈
关键词
激光诱导击穿光谱技术
中药质量评价
多元素检测
laser-induced breakdown spectroscopy(LIBS)
traditional Chinese medicine evaluation
multi-element analysis
