摘要
电镜观察42例急性缺血性脑卒中、20例高血压及20名健康成人的血小板聚集物(%)和每一聚集物内的血小板个数。结果急性缺血性脑卒中组分别为31.06±13.54和128.95±67.02,高血压组分别为16.18±7.89和50.70±28.68,健康人组分别为5.93±3.10和16.20±8.35,三组相比有显著差异。但在急性缺血性脑卒中病例中,脑血栓与TIA相比,无明显差异。认为血小板聚集性增高是急性缺血性脑卒中发病的重要因素,尤以长期高血压患者,如血小板聚集性增高,可作为脑血栓及TIA的危险信号。
Electron microscopic study of the percentage of platelet aggregation and the average number of platelets in an aggregate in 42 cases of acute cerebral ischemic stroke, 20 cases of hypertension and 20 normal subjects revealed 31.06±13.54% and 128.95±67.02, 16.18±7.89% and 50.70±28.68, and 5.39±3.10% and 16,20±8.35 respectively. There was pronounced difference between these 3 groups, but no significant difference was found in the patients with cerebral thrombosis(32 cases) and transient ischemic attack(10 cases) in the group of acute ischemic stroke. We believe that the platelet hyperactivity is an important factor in the pathogenesis of actrte cerebral ischemic stroke. In patients with long-term hypertension, the increase of platelet aggregation may be considered as a possible risk factor in the development of cerebral thrombosis and transient ischemic attack.
出处
《上海医学》
CAS
1983年第6期316-318,共3页
Shanghai Medical Journal