摘要
目的探讨中性粒细胞与淋巴细胞比值(NLR)、淋巴细胞与单核细胞比值(LMR)、血小板与淋巴细胞比值(PLR)预测慢性鼻窦炎鼻内镜术后复发价值。方法选取2016年3月至2018年3月收治的慢性鼻窦炎鼻内镜治疗患者60例。所有患者均术后随访6个月,并根据鼻窦炎是否复发分为术后复发组(n=21)和术后未复发组(n=39)。同期选取87例健康体检者作为对照组(n=87)。收集并分析所有患者NLR、LMR、PLR数值,并绘制上述指标受试者工作特征曲线(ROC)。结果CRS组NLR、PLR水平高于对照组,差异具有统计学意义(P<0.05);CRS组LMR水平低于对照组,差异具有统计学意义(P<0.01);术后未复发组NLR、LMR、PLR水平与对照组差异无统计学意义(P>0.05);术后复发组NLR、PLR水平高于术后未复发组,差异具有统计学意义(P<0.05);术后复发组LMR水平低于术后未复发组,差异具有统计学意义(P<0.01);NLR的敏感度、特异度分别为63.33%(19/30)、93.33%(28/30);LMR的敏感度、特异度分别为72.00%(18/25)、91.43%(32/35);PLR的敏感度、特异度分别为67.86%(19/28)、93.75%(30/32);ROC曲线显示:NLR、LMR、PLR曲线下面积分别为0.719(0.587~0.851)、0.922(0.853~0.991)、0.830(0.587~0.851)。结论NLR、LMR、PLR能较好地预测慢性鼻窦炎鼻内镜术后复发情况。
Objective To explore the value of the neutrophil to lymphocyte ratio(NLR),lymphocyte to monocyte ratio(LMR),and platelet to lymphocyte ratio(PLR)in predicting the recurrence of chronic sinusitis after endoscopic sinus surgery.Methods Sixty patients with chronic sinusitis treated by endoscopy from March 2016 to March 2018 were selected.All patients were followed up for 6 months and were divided into the postoperative recurrence group(n=21)and non-postoperative recurrence group(n=39)according to whether sinusitis recurred or not.In the same period,87 people who underwent a health examination at our hospital were selected as the control group(n=87).The NLR,LMR and PLR of all patients were collected and analyzed.The receiver operating characteristic curve(ROC)of the above indicators was drawn.Results The NLR and PLR levels in the chronic rhinosinusitis(CRS)group were higher than those in the control group(p<0.05).The level of LMR in the CRS group was lower than that in the control group(p<0.01).There was no significant difference in NLR,LMR and PLR between the non-postoperative recurrence group and the control group(p>0.05).The levels of NLR and PLR in the postoperative recurrence group were higher than those in the non-postoperative recurrence group(p<0.05).The level of LMR in the postoperative recurrence group was lower than that in the non-postoperative recurrence group(p<0.01).The sensitivity and specificity of NLR were 63.33%(19/30)and 93.33%(28/30),respectively.The sensitivity and specificity of LMR were 72.00%(18/25)and 91.43%(32/35),respectively.The sensitivity and specificity of PLR were 67.86%(19/28)and 93.75%(30/32),respectively.The ROC curves showed that the areas under NLR,LMR and PLR curves were 0.719(0.587-0.851),0.922(0.853-0.991),and 0.830(0.587-0.851),respectively.Conclusion NLR,LMR and PLR can help to predict chronic sinusitis recurrence after endoscopic sinus surgery.
作者
谢书华
杨竹梅
刘慧茹
董晶
XIE Shuhua;YANG Zhumei;LIU Huiru;DONG Jing(Department of Otorhinolaryngology,Shanghai Yangpu District Kongjiang Hospital,Shanghai 200093,China;Department of Otorhinolaryngology Head and Neck Surgery,Yangpu Hospital affiliated to Tongji University,Shanghai 200090,China)
出处
《山东大学耳鼻喉眼学报》
CAS
2020年第1期54-57,共4页
Journal of Otolaryngology and Ophthalmology of Shandong University
