摘要
目的:观察调和阴阳法针灸结合穴位按摩对顽固性失眠症患者日间嗜睡症状及焦虑症状的改善作用。方法:选择152例顽固性失眠患者,按随机数字表法分为观察组与对照组各76例。对照组接受西医常规治疗,观察组在对照组基础上应用调和阴阳法针灸结合穴位按摩治疗。比较2组临床疗效及不良反应,比较2组治疗前后中医证候积分、日间嗜睡症状、5-羟色胺(5-HT)、γ-氨基丁酸(GABA)水平及焦虑症状改善情况。结果:治疗后,观察组治疗总有效率96.05%,高于对照组86.84%(P<0.05)。治疗前,2组入寐困难、寐而易醒、醒后不寐、躁乱多梦等中医证候积分比较,差异无统计学意义(P>0.05);治疗后,2组上述中医证候积分均降低(P<0.05),且观察组低于对照组(P<0.05)。治疗前,2组Epworth嗜睡量表评分及焦虑自评量表(SAS)评分比较,差异无统计学意义(P>0.05);治疗后,2组Epworth嗜睡量表评分及SAS评分均降低(P<0.05),且观察组低于对照组(P<0.05)。治疗前,2组血清5-HT、GABA水平比较,差异无统计学意义(P>0.05);治疗后,2组血清5-HT、GABA水平均升高(P<0.05),且观察组高于对照组(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:调和阴阳法针灸结合穴位按摩治疗顽固性失眠疗效确切,可改善失眠症状、日间嗜睡症状、焦虑症状及体内神经递质水平,且安全性较好。
Objective:To observe the improvement effect of acupuncture and moxibustion of yin-yang harmony method combined with point massage on symptoms of daytime sleepiness and anxiety in patients with intractable insomnia.Methods:A total of 152 cases of patients with intractable insomnia were selected and divided into the observation group and the control group according to the random number table method,with 76 cases in each group.The control group was treated with routine western medicine,and the observation group was additionally treated with acupuncture and moxibustion of yin-yang harmony method combined with point massage based on the treatment of the control group.The clinical effects and adverse reactions were compared between the two groups.Before and after treatment,the improvement of traditional Chinese medicine(TCM)syndrome scores,daytime sleepiness,levels of 5-hydroxytryptamine(5-HT)andγ-aminobutyric acid(GABA),and anxiety was compared between the two groups.Results:After treatment,the total effective rate was 96.05%in the observation group,higher than that of 86.84%in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of the scores of TCM syndromes including difficult to sleep,easy to wake up,insomnia after waking up,and agitation disorders and profuse dreaming between the two groups(P>0.05).After treatment,the above TCM syndrome scores in the two groups were decreased(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of the scores of Epworth Sleepiness Scale and Selfrating Anxiety Scale(SAS)between the two groups(P>0.05).After treatment,the scores of Epworth Sleepiness Scale and SAS were decreased(P<0.05),and the scores in the observation group were lower than those in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparison of levels of 5-HT and GABA in serum between the two groups(P>0.05).After treatment,the levels of 5-HT and GABA in serum in the two groups were increased(P<0.05),and the levels in the observation group were higher than those in the control group(P<0.05).There was no significant difference being found in the comparison of incidence of adverse reactions between the two groups(P>0.05).Conclusion:Acupuncture and moxibustion of yin-yang harmony method combined with point massage has a definite curative effect in treating intractable insomnia,and can improve symptoms of insomnia,daytime sleepiness and anxiety,and levels of neurotransmitters in the body,with good safety.
作者
王秋萍
沈慧萍
付康
WANG Qiuping;SHEN Huiping;FU Kang(Department of Severe Psychiatry,Shaoxing Seventh People's Hospital,Shaoxing Zhejiang 312000,China)
出处
《新中医》
CAS
2023年第13期151-155,共5页
New Chinese Medicine
关键词
顽固性失眠症
调和阴阳法
针灸
穴位按摩
日间嗜睡症状
焦虑症状
Intractable insomnia
Yin-yang harmony method
Acupuncture and moxibustion
Point massage
Daytime sleepiness
Anxiety symdtom
