摘要
目的分析新疆疏附县2018年维吾尔族健康人群麻疹抗体水平及其影响因素,为针对性制定麻疹防控策略提供依据。方法采用分层抽样方法选择调查对象,收集基本资料信息,并采集血样标本检测麻疹IgG抗体水平。采用单因素和多因素logistic回归分析麻疹抗体的相关因素。结果共调查3001名维吾尔族健康人群,其中麻疹抗体阳性率为89.10%(2674/3001),抗体保护率为45.55%(1367/3001),抗体几何平均浓度(GMC)为843.33 mIU/mL。0~1岁和>14岁的人群麻疹抗体阳性率分别为72.81%、83.96%,低于其他年龄组,不同年龄组麻疹抗体阳性水平差异有统计学意义(χ^(2)=114.17,P<0.001)。有麻疹疫苗接种史的人群抗体阳性率和抗体保护率分别为90.41%、46.24%,均高于无麻疹疫苗接种人群,差异均有统计学意义(χ^(2)=3.84、35.23,P均<0.05)。2011-2016年麻疹发病率中或高的乡镇人群较低发乡镇的人群抗体阳性率更高,差异有统计学意义(χ^(2)=6.05,P<0.05)。结论疏附县政府在重点做好新生儿含麻疹成份疫苗(MV)常规免疫的同时,还应加强成人MV预防接种工作,巩固麻疹低发乡镇的疫情防控成果,提高免疫接种比例。
Objective To determine measles antibody levels and influencing factors among healthy Uygur population in Shufu county of Xinjiang province in 2018,and provide basis for prevention and control strategies of measles.Methods Stratified sampling method was used to select subjects for collection of basic information.Blood samples were obtained for testing measles IgG antibody levels.Univariate and multivariate logistic regression were used to analyze the relative factors of measles antibody.Results Among 3001 subjects,the antibody positive rate was 89.10%for a protection rate of 45.55%;and the geometric mean concentration(GMC)was 843.33 mIU/mL.Measles antibody positive rates were lower in 0-1 and>14 years old.People who had been vaccinated against measles and who had a higher incidence of measles from 2011 to 2016 had higher positive rates of measles antibody detection.Conclusion The government of Shufu county should not only focus on routine immunization of neonatal measles vaccine(MV)but also strengthen the preventive inoculation of adult MV,consolidating achievements in epidemic prevention and control of villages with low measles incidence,and improve the proportion of immunization.
作者
刘文辉
刘媛媛
范淑君
张周斌
袁俊
杨智聪
沈纪川
薛振香
周自严
LIU Wen-hui;LIU Yuan-yuan;FAN Shu-jun;ZHANG Zhou-bin;YUAN Jun;YANG Zhi-cong;SHEN Ji-chuan;XUE Zhen-xiang;ZHOU Zi-yan(Guangzhou Centre for Disease Control and Prevention,Guangzhou,Guangdong 510440,China;Baiyun District Center for Disease Control and Prevention,Guangzhou,Guangdong 510440,China;Shufu County Center for Disease Control and Prevention,Kashgar,Xinjiang 844100,China)
出处
《热带医学杂志》
CAS
2023年第1期109-113,共5页
Journal of Tropical Medicine
基金
广州市科技计划项目(201704020004)
关键词
麻疹
抗体
健康人群
影响因素
Measles
Antibody
Healthy population
Influencing factors
