摘要
目的调查重庆市4个区县的新型冠状病毒肺炎无症状感染者和确诊病例的密切接触者在不同暴露状态下受感染的情况,进一步探讨新型冠状病毒肺炎密切接触者的流行病学特征与感染危险因素。方法纳入调查对象2670名,共119名密切接触者转为感染者,其中确诊病例72人,无症状感染者47人。使用Excel 2017对数据进行分类清洗、梳理,采用SPSS 25.0进行统计分析。结果密切接触者总感染率为4.47%(119/2670)。确诊病例的感染率为4.68%(109/2329),无症状感染者的感染率为2.93%(10/341),差异无统计学意义(χ^(2)=0.412,P=0.521)。119例感染者中94例(78.99%)与关联病例为亲属关系,21例(17.65%)为社交活动关系,4例(3.36%)为其他关系。与关联病例最主要的接触地点在家中,占82.35%(98/119)。主要的接触方式为同餐、同住和其他,分别为81.51%(97/119)、5.04%(6/119)、13.45%(16/119)。密切接触者中感染者在不同的关联病例关系、不同接触频率、不同接触方式、不同接触地点以及不同暴露时间之间的差异具有统计学意义(P<0.05)。Logistic多因素回归分析发现,密切接触者与关联病例经常接触(OR=4.366,95%CI:2.417~7.886),接触地点为娱乐场所(OR=3.921,95%CI:1.058~14.540)为密切接触感染的危险因素。结论密切接触者的管控是疫情防控的重要环节,及早发现密切接触者中的感染者,执行严格的隔离措施和加强娱乐场所的个人防护和场所管控是减少被感染风险的有效防护措施。
Objective To investigate the epidemiological characteristics and risk factors of close contacts of coronavirus disease 2019(COVID-19).Methods A total of 2670 people with close contacts of confirmed COVID-19 were enrolled.A total of 119 close contacts became infected,including 72 confirmed cases and 47 asymptomatic infections.Logistic regression analysis model was used to explore contact infection.Results The total infection rate was 4.47%(119/2670).The infection rates of confirmed cases and positive contacts were 4.68%(109/2329)and 2.93%(10/341),respectively.The difference was not statistically significant(χ^(2)=0.412,P=0.521).Among all the contacts,119 were infected,21 cases(17.65%)were social activities,4 cases(3.36%)were his relationship.98(82.35%)were exposed to the infectors in family getherings;and 97(81.51%),6(5.04%),and 16(13.45%)were reported dining,living or with other ways.Among the close contacts,the infected persons have different related case relationships and different contact frequencies.There were statistically significant differences among different exposure methods,different exposure locations and different exposure times(P<0.05).Logistic regression analysis revealed frequent contact(OR=4.366,95%CI:2.417-7.886)and places of entertainment(OR=3.921,95%CI:1.058-14.540)were risk factors.Conclusion s The control of close contacts should be an important part of epidemic prevention and control.Early detection of infected people among close contacts,implementation of strict isolation measures,and strengthening of personal protection and distance control in entertainment venues should be effective protects.
作者
贺安然
唐晓君
张勇
邱景富
杨森评
陈林
罗超
HE An⁃ran;TANG Xiao⁃jun;ZHANG Yong;QIU Jing⁃fu;YANG Sen⁃ping;CHEN Lin;LUO Chao(Wanzhou District Center for Disease Control and Prevention,Chongqing 404000;School of Public Health,Chongqing Medical University,Chongqing 400016;Yubei District Center for Disease Control and Prevention,Chongqing 401120;Hechuan District Center for Disease Control and Prevention,Chongqing 401520,China)
出处
《热带医学杂志》
CAS
2022年第7期1022-1025,共4页
Journal of Tropical Medicine
基金
重庆市启动科研应急攻关项目
