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盐酸氢吗啡酮用于全身麻醉诱导的临床研究 被引量:3

Clinical Study of Hydromorphone Hydrochloride in Induction of General Anesthesia
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摘要 目的探讨全身麻醉诱导中盐酸氢吗啡酮应用的临床效果。方法选取2019年5月—2019年10月期间我院的60例手术患者作为此次研究对象。患者手术时均进行全身麻醉,将其随机分为对照组30例(使用0.4μg/kg舒芬太尼进行全麻诱导)和研究组30例(使用0.03 mg/kg盐酸氢吗啡酮进行全麻诱导),将两组应用效果进行对比。结果术后,研究组患者出现不良反应几率(13.33%)明显低于对照组(40.00%);研究组患者麻醉满意度(96.67%)明显优于对照组(66.67%),研究组清醒时间与对照组相比明显更短,P<0.05,组间对比差异具有统计学意义。结论全身麻醉诱导中使用适当剂量的盐酸氢吗啡酮具有明显优势,能降低术后出现恶心呕吐、耳鸣、瘙痒、红疹及寒颤等不良反应发生率,安全性较好。 Objective To explore the clinical effect of hydromorphone hydrochloride in general anesthesia induction.Methods Sixty surgical patients in our hospital from May 2019 to October 2019 were selected as the subjects of this study.All patients were induced by general anesthesia during operation.They were randomly divided into control group(30 cases were induced by Sufentanill at 0.4μg/kg)and research group(30 cases were induced by hydromorphone at 0.03 mg/kg).The effects of the two groups were recorded and compared.Results Postoperatively,the incidence of adverse reactions(13.33%)in the study group was significantly lower than that in the control group(40.00%);the satisfaction of anesthesia in the study group(96.67%)was significantly better than that in the control group(66.67%),the study group spent significantly less time awake than the control group,and the difference between the two groups was statistically significant(P<0.05).Conclusion Appropriate dosage of hydromorphone hydrochloride has obvious advantages in induction of general anesthesia.It can reduce the incidence of adverse reactions such as nausea and vomiting,tinnitus,pruritus,rash and chills after operation and It is safe.
作者 李颖 LI Ying(Department of Anesthesiology,Jilin Provincial People's Hospital,Changchun Jilin 130021,China)
出处 《中国卫生标准管理》 2020年第3期128-130,共3页 China Health Standard Management
关键词 全身麻醉诱导 盐酸氢吗啡酮 舒芬太尼 不良反应 麻醉满意度 清醒时间 安全性 general anesthesia induction hydromorphone hydrochloride sufentanil adverse reactions anesthesia satisfaction awake time safety
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