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耐力夫外用延时喷剂治疗早泄的临床研究

Clinical study on the treatment of premature ejaculation with Nailifu Spray
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摘要 目的:观察耐力夫外用延时喷剂对早泄治疗的效果。方法:2022年1月1日至2023年1月1日,共90例患者纳入此项研究。采用耐力夫外用延时喷剂喷涂阴茎皮肤表面,每天1次,1次2喷,持续4周。并分别于治疗前、治疗后采集患者早泄诊断工具(PEDT)得分、阴道内射精潜伏时间(IELT)、国际勃起功能指数-5(IIEF-5)得分。结果:治疗前PEDT的中位数(P25,P75)为16.0(15.0,18.0)分,治疗后为10.0(10.0,10.0)分。治疗前IELT的中位数(P25,P75)为20.0(10.0,30.0)s,治疗后为240.0(180.0,300.0) s。治疗前IIEF-5的中位数(P25,P75)为21.0(21.0,22.0)分,治疗后为21.0(21.0,21.0)分。与基线水平相比,IELT时间明显延长,PEDT评分明显降低,差异具有统计学意义。IIEF-5评分未见明显改变。结论:耐力夫外用延时喷剂治疗早泄确切有效,值得临床推广。 Objective:To observe the effect of Nailiju Spray on the treatment of premature ejaculation.Methods:A total of 90 patients were included in this study from January 1,2022 to January 1,2023.Nailifu spray was used to spray the surface of penile skin once a day,2 sprays per session for 4 weeks.And the patients'premature ejaculation diagnostic tool(PEDT)scores,intravaginal ejaculation latency time(IELT),and international index of erectile function-5(IIEF-5)scores were collected before and after treatment,respectively.Resuts:The median(P25,P75)PEDT scores was 16.0(15.0,18.0)scores before treatment and 10.0(10.0,10.0)scores after treatment.The median(P25,P75)of IELT was 20.0(10.0,30.0)s before treatment and 240.0(180.0,300.0)s after treatment.The median(P25,P75)of IIEF-5 scores was 21.0(21.0,22.0)scores before treatment and 21.0(21.0,21.0)scores after treatment.Compared with baseline levels,IELT was significantly longer and PEDT scores were significantly lower,with statistically significant differences.No significant changes in IIEF-5 scores were seen.Conclusion:Nailifu spray treatment of premature ejaculation is accurate and effective,worthy of clinical promotion.
作者 王品骁 李军涛 陈善闻 袁稼芮 孙翔 陈望强 赵大伟 冯建勇 张运涛 王延柱 高明 WANG Pin-xiao;LI Jun-tao;CHEN Shan-wen;YUAN Jia-rui;SUN Xiang;CHEN Wang-qiang;ZHAO Da-wei;FENG Jian-yong;ZHANG Yun-tao;WANG Ting-zhu;GAO Ming(Department of Urology,Xian Daxing Hospital,Yanan University,Xi'an,Shaanxi 710016,China;Department of Urology,Jinan Central Hospital,Jinan,Shandong 250013,China;Department of Urology,Huashan Hospital,Fudan University,Shanghai 200040,China;Xijing Hospital,Air Force Medical University,Xi'an,Shaanxi 710032,China;Department of Urology,First Affiliated Hospital of Nanchang University,Nanchang,Jiangxi 330006,China;Department of Urology,Hangzhou Red Cross Hospital,Hangzhou,Zhejiang 310005,China)
出处 《中华男科学杂志》 CAS CSCD 北大核心 2023年第8期725-728,共4页 National Journal of Andrology
基金 陕西省卫生健康委员会一般项目(2022D006) 西安市英才计划青年人才项目(XAYC211060) 西安市科技计划项目(2022JHYBYJ-0399,23YXYJ0112) 陕西省科协省级学会主题科普活动(2023-2-1-3)的支持
关键词 耐力夫外用延时喷剂 早泄 早泄诊断工具 阴道内射精潜伏时间 国际勃起功能指数-5 Nailifu spray premature ejaculation premature ejaculation diagnostic tool intravaginal ejaculation latency time international index of erectile function-5
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