摘要
膀胱尿路上皮癌是常见的泌尿系统肿瘤之一,对于肌层浸润性膀胱癌,根治性膀胱全切术+化疗是目前标准治疗方案。膀胱全切是极为复杂的泌尿外科手术,有着较高的围术期并发症发生率和二次手术的风险,也会一定程度影响患者术后的生活质量。膀胱部分切除术作为曾经较常见的手术方式重新进入到人们的视野,早期部分回顾性研究证实在部分患者中由于肿瘤特点不适宜行膀胱部分切除术导致了较高的复发率,近年来随着研究的进展发现,如果能严格把控手术指征,能够有效地降低部分切除术后肿瘤的复发率。目前常用的膀胱部分切除手术方式包括腹腔镜膀胱部分切除术、机器人辅助膀胱部分切除术与传统的开放膀胱部分切除术。同时,手术联合术前新辅助或术后辅助治疗也是膀胱部分切除术的发展方向。对于一些曾经需行膀胱根治性切除术的患者,膀胱部分切除术也成为可选择的手术方案。本文将对膀胱尿路上皮癌的膀胱部分切除术研究进展进行归纳和总结。
Bladder urothelial carcinoma is one of the common urological tumors.For muscle invasive bladder cancer,radical cystectomy and chemotherapy is the current standard treatment.Radical cystectomy is the most complicated urological surgery,with a high risk of complications and secondary surgery,which also affected the quality of life after surgery.Partial cystectomy has been used as a once common surgery.Early a part of retrospective studies have caused a high recurrence rate because some patients were not suitable for partial cystectomy.If the surgical indications can be strictly controlled,the postoperative recurrence rate can be controlled.At present,the commonly used partial cystectomy includes laparoscopic partial cystectomy,robotic partial cystectomy and open partial cystectomy.Neoadjuvant therapy and adjuvant therapy are also the development direction of partial cystectomy.Partial cystectomy is an option for some patients who plan to perform radical cystectomy.This review will summarize the research progress of partial cystectomy for bladder urothelial carcinoma.
作者
纪永鹏
王硕
杜鹏
Ji Yongpeng;Wang Shuo;Du Peng(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Department of Urology,Peking University Cancer Hospital&Institute,Beijing 100142,China)
出处
《泌尿外科杂志（电子版）》
2022年第4期58-62,共5页
Journal of Urology for Clinicians(Electronic Version)
关键词
膀胱癌
膀胱部分切除术
新辅助治疗
辅助治疗
Bladder cancer
Partial cystectomy
Neoadjuvant therapy
Adjuvant therapy
