摘要
注意力缺陷多动障碍是一种常见的以神经系统发育缺陷为特征的异质性疾病,病机复杂。通过多年研究,病因尚不完全清楚,此病初期主要表现以心肝火旺为主,中、后期主要以脾肾两虚为主。该研究主要以脑-肠轴为轴索基础,探讨多动症(心肝有余,脾肾不足)发病风险或表现相关不同因素组成变化,以及在其他机制如脑-肠轴在多动症发病的作用,分别从生理和病理状态下论治脑肠轴和多动症的关系,以肠道菌群为链接点,以肠道微生物群落为关键调节器,在中医理论体系中,通过"脾肾多气虚、心肝多阴虚"的气阴两虚型来辨证治疗,结合脑肠轴理论与注意力缺陷多动障碍的研究,为拓展脑-肠轴相关疾病防治提供理论与临床指导。
Attention deficit hyperactivity disorder is a common heterogeneous disease characterized by nervous system development defects,with complex pathogenesis.Through years of research,the etiology is not completely clear.The disease is mainly characterized by exuberant heart and liver fire in the early stage,and spleen and kidney deficiency in the middle and late stages.In this study,the brain-gut axis was used as the basis of the axon to discuss the changes in the composition of different factors related to the risk or manifestations of hyperactivity disorder(excess of liver and kidney,and deficiency of spleen and kidney)and the role of the brain-gut axis in the pathogenesis of hyperactivity syndrome.The relationship between the brain-gut axis and hyperactivity disorder was treated from the physiological and pathological states,respectively.with the intestinal flora as the linking point,and the intestinal microbial community as the key regulator,in the theoretical system of traditional Chinese medicine,the Qi and Yin deficiency syndrome of“spleen and kidney deficiency of Qi,and heart and liver deficiency of Yin”was treated in a differentiated manner,which combined with the brain-gut axis theory and the study of attention deficit hyperactivity disorder to expand the brain-gut.
作者
张宇
刘玉堂
罗原
张玲
ZHANG Yu;LIU Yutang;LUO Yuan;ZHANG Ling(Shaanxi University of Traditional Chinese Medicine,Xi'an 712046,Shaanxi,China;Xi'an Traditional Chinese Medicine Encephalopathy Hospital,Xi'an 710032,Shaanxi,China)
出处
《辽宁中医药大学学报》
CAS
2021年第11期120-124,共5页
Journal of Liaoning University of Traditional Chinese Medicine
基金
国家中医药管理局中医药标准化项目[SATCM-2015-BZ(231)]
陕西省中医药重点研究室:西安中医脑病医院脑病中医药研究室项目[陕中医药函(2013)229号]
中医药传承和创新“百千万”人才工程(岐黄工程)(陕西中医药函[2019]237号)
关键词
注意力缺陷多动障碍
心肝有余
脾肾不足
脑-肠轴
肠道菌群
论治
attention deficit hyperactivity disorder
excess of heart and liver
insufficient spleen and kidney
brain-intestine axis
intestinal flora
treatment
