摘要
目的:分析医院普外科患者术后并发腹腔感染的病原菌分布与耐药特点,为临床患者术后腹腔感染的防治提供参考。方法:选取2019年8月—2021年8月黄冈市黄州区人民医院普外科收治的102例术后并发腹腔感染的患者作为研究对象,分析患者腹腔穿刺液标本中病原菌的分布和主要病原菌的耐药情况。结果:102例患者送检标本中共分离出病原菌128株,其中革兰阴性菌79株(占61.72%,以大肠埃希菌、鲍曼不动杆菌、肺炎克雷伯菌为主)、革兰阳性菌43株(占33.59%,以粪肠球菌为主)和真菌6株(占4.69%);药敏结果显示,大肠埃希菌和肺炎克雷伯菌对哌拉西林-他唑巴坦钠、米诺环素、妥布霉素、阿米卡星、亚胺培南、替加环素、头孢哌酮-舒巴坦钠的耐药率均较低(<30.00),鲍曼不动杆菌仅对左氧氟沙星、米诺环素、阿米卡星、替加环素的耐药率较低(<30.00%);屎肠球菌仅对万古霉素、利奈唑胺、莫西沙星、利福平的耐药率较低(<30.00%)。结论:医院普外科患者术后并发腹腔感染的病原菌主要为革兰阴性菌,但革兰阳性菌也有较多检出,临床在选用抗菌药物治疗时应尽量参考微生物培养及其药敏试验结果,以保证对患者的治疗效果。
Objective:To analyze pathogenic bacteria distribution and drug resistance in postoperative complication of abdominal infections in patients in general surgery department of a hospital,and to provide reference for prevention and treatment on postoperative abdominal infections of clinical patients.Methods:102 patients with postoperative complication of abdominal infections,admitted to the general surgery department of Huangzhou District People’s Hospital,Huanggang from August 2019 to August 2021,were selected as study subjects,and the distribution of pathogenic bacteria in abdominal puncture fluid specimens of the patients and the drug resistance of major pathogenic bacteria were analyzed.Results:A total of 128 strains of pathogenic bacteria were isolated from submitted specimens of 102 patients,including 79 strains of Gram-negative bacteria(accounting for 61.72%,mainly Escherichia coli,Acinetobacter baumannii and Klebsiella pneumoniae),43 strains of Gram-positive bacteria(accounting for 33.59%,mainly Enterococcus faecalis)and 6 strains of fungi(accounting for 4.69%).The drug susceptibility test showed that the resistance rates of Escherichia coli and Klebsiella pneumoniae to piperacillin-tazobactam sodium,minocycline,tobramycin,amikacin,imipenem,tigecycline,cefoperazone-sulbactam sodium were low(less than 30.00%),while the resistance rate of Acinetobacter baumannii only to levofloxacin,minocycline,amikacin and tigecycline was low(less than 30.00%),and the resistance rate of Enterococcus faecalis only to vancomycin,linezolid,moxifloxacin and rifampin was low(less than 30.00%).Conclusion:The pathogenic bacteria in postoperative complication of abdominal infections in patients in general surgery department of the hospital are mainly Gram-negative bacteria,but Gram-positive bacteria are also detected more often,so antibacterial drugs should be clinically selected with reference to the results of microbial culture and drug susceptibility test as far as possible to ensure the therapeutic effect on patients.
作者
邵懿
SHAO Yi(General Surgery Department I,Huangzhou District People's Hospital,Huanggang Hubei 438000,China)
出处
《抗感染药学》
2022年第7期960-963,共4页
Anti-infection Pharmacy
关键词
腹腔感染
病原菌分布
耐药特点
普外科
abdominal infection
distribution of pathogenic bacteria
drug resistance characteristic
general surgery department
