摘要
目的:研究孟鲁司特钠联合中药雾化吸入治疗小儿支气管肺炎的疗效及安全性。方法:选取2017年11月-2018年11月开封市儿童医院接诊的100例支气管肺炎呼吸疾病儿童患者作为研究对象,按照治疗方法的不同,将患儿均分为单一组和联合组,每组50例。两组患儿均进行常规治疗,单一组患儿在常规治疗的基础上使用孟鲁司特钠治疗,联合组在单一组患儿治疗的基础上联用中药雾化吸入治疗。比较两种治疗方法的临床效果;统计两组患儿的退热时间、咳嗽消失时间、湿啰音消失时间、住院天数等临床指标;记录两组患儿在治疗期间出现的恶心呕吐、皮疹、肝功能异常、胃肠道反应等不良反应。结果:联合组患儿治疗的总有效率为90%,显著高于单一组患儿的72%(P<0.05);联合组患儿退热时间、咳嗽消失时间、湿啰音消失时间、住院天数等各项指标明显低于单一组患儿(P<0.05);联合组患儿治疗期间发生不良反应发生率为12%,与单一组的8%比较差异无统计学意义(P>0.05)。结论:利用孟鲁司特钠联合中药雾化吸入治疗小儿支气管肺炎,疗效更佳,能显著缩短各项症状消失时间和住院天数,且具有较高的安全性,值得在临床推广应用。
Objective:To investigate the efficacy and safety of montelukast sodium combined with traditional Chinese medicine atomization inhalation in the treatment of children with bronchopneumonias.Methods:A total of 100 children with bronchial pneumonia who were treated in Kaifeng Children’s Hospital from June 2017 to June 2018 were enrolled in this study.According to different treatment methods,100 children were divided into single groups and combined group,50 children in each group.Children in both groups received routine treatment,montelukast sodium treatment was used on the basis of routine treatment in the single group,and Chinese medicine atomization inhalation treatment was used on the basis of treatment in the combined group.Compare the clinical effect of the two treatment methods.Clinical indicators such as antipyretic time,cough disappearance time,wet-rafter disappearance time and hospitalization time were counted.Nausea,vomiting,rash,abnormal liver function,gastrointestinal reactions and other adverse reactions during treatment were recorded in the two groups.Results:The total effective rate of the combined group was 90%,significantly higher than that of the single group(P<0.05).The antipyretic time,cough disappearance time,wet rale disappearance time and hospitalization time in the combined group were significantly lower than those in the single group(P<0.05).The incidence of adverse reactions during treatment in the combined group was 12%,which was not statistically significant compared with 8%in the single group(P>0.05).Conclusions:Montelukast sodium combined with traditional Chinese medicine atomization inhalation in the treatment of children bronchopneumonias has better efficacy,can significantly shorten the time of symptom disappearance and hospital stay,and has a high safety,worthy of clinical application.
作者
高慧
赵恵雅
GAO Hui;ZHAO Huiya(Seven Departments in Kaifeng Children's Hospital,Kaifeng 475000,China)
出处
《包头医学院学报》
CAS
2021年第12期35-38,共4页
Journal of Baotou Medical College
关键词
孟鲁司特钠
中药雾化吸入
支气管肺炎
儿童
montelukast sodium
Chinese medicine atomization inhalation
combination therapy
therapeutic effect
safety
