摘要
目的探究个体化医学营养疗法与运动疗法联合门冬胰岛素在妊娠期糖尿病(GDM)患者中的应用效果.方法选取本院2019年5月—2022年5月收治的106例GDM患者,按照随机数字表法分为对照组和观察组,每组53例.对照组采用门冬胰岛素治疗,观察组在对照组基础上采取个体化医学营养疗法联合运动疗法,均持续治疗至患者分娩.比较两组胰岛素抵抗、脂肪因子水平、妊娠结局.结果治疗前,两组胰岛素抵抗指标、脂肪因子水平比较,组间差异无统计学意义(P>0.05);治疗后,观察组空腹胰岛素水平(8.38±1.03)mIU/L、胰岛素抵抗指数(1.77±0.35)均低于对照组,脂联素水平(15.66±1.73)mg/L、网膜素水平(78.35±7.88)ng/L均高于对照组,内脂素水平(7.35±0.93)ng/L低于对照组,不良妊娠结局发生率7.55%低于对照组,组间差异有统计学意义(P<0.05).结论个体化医学营养疗法与运动疗法结合门冬胰岛素能够有效减轻GDM患者胰岛素抵抗,调节脂肪因子水平,降低不良妊娠结局发生风险.
Objective To explore the application effect of individualized medical nutrition therapy and exercise therapy combined with insulin aspart in patients with gestational diabetes mellitus(GDM).Methods 106 patients with GDM admitted to the hospital from May 2019 to May 2022 were selected and divided into a control group and an observation group,with 53 cases in each group.The control group was treated with insulin aspart,and the observation group was treated with individualized medical nutrition therapy combined with exercise therapy on the basis of the control group,all of which continued until the patient gave birth.The insulin resistance,adipokine level and pregnancy outcome were compared between the two groups.Results Before treatment,there were no significant differences in insulin resistance indexes and adipokines levels between the two groups(P>0.05);after treatment,fasting insulin level(8.38±1.03)mIU/L and insulin resistance index(1.77±0.35)in the observation group were lower than those in the control group,and adiponectin level(15.66±1.73)mg/L and chemerin level(78.35±7.88)ng/L were higher than those in the control group,visfatin level(7.35±0.93)ng/L was lower than that in the control group,and the incidence of adverse pregnancy outcome 7.55%was lower than that in the control group,with statistically significant differences between the groups(P<0.05).Conclusion Individualized medical nutrition therapy and exercise therapy combined with insulin aspart can effectively reduce insulin resistance,regulate the level of adipokines and reduce the risk of adverse pregnancy outcomes in patients with GDM.
作者
车海云
CHE Haiyun(Department of Internal Medicine,Maternal and Child Health Hospital,Linxia Hui Autonomous Prefecture,Gansu Province,Linxia Gansu,731100,China)
出处
《反射疗法与康复医学》
2023年第2期136-138,142,共4页
Reflexology And Rehabilitation Medicine
关键词
妊娠期糖尿病
医学营养疗法
门冬胰岛素
胰岛素抵抗
脂肪因子
妊娠结局
Gestational diabetes mellitus
Medical nutrition therapy
Insulin aspart
Insulin resistance
Fat factor
Pregnancy outcome
