摘要
目的探讨重复经颅磁刺激联合药物治疗在精神分裂症患者中的应用效果.方法选取2020年2月—2022年3月该院收治的74例精神分裂症患者为研究对象,按随机数字表法分为两组.对照组(n=37)采用药物治疗,观察组(n=37)在对照组基础上联合重复经颅磁刺激治疗.对比两组临床疗效、认知功能及睡眠质量.结果观察组临床总有效率为94.59%,高于对照组的78.38%,差异有统计学意义(P<0.05).观察组治疗后简易精神状态检查表评分为(22.40±3.48)分,高于对照组的(18.25±3.30)分,差异有统计学意义(P<0.05).观察组治疗后匹兹堡睡眠质量指数中的睡眠开始时间、睡眠时间、睡眠效率、睡眠质量、睡眠障碍、催眠药物、日间功能障碍评分分别为(1.33±0.07)分、(1.24±0.10)分、(0.80±0.08)分、(1.02±0.07)分、(1.02±0.05)分、(1.12±0.08)分、(1.12±0.15)分,均低于对照组的(1.62±0.10)分、(1.70±0.15)分、(1.12±0.10)分、(1.34±0.09)分、(1.33±0.07)分、(1.46±0.10)分、(1.60±0.18)分,组间差异有统计学意义(P<0.05).结论重复经颅磁刺激联合药物治疗在精神分裂症患者中的应用效果显著,能够有效改善其认知功能,提升其睡眠质量.
Objective To explore the application effect of repetitive transcranial magnetic stimulation combined with drug therapy in patients with schizophrenia.Methods 74 patients with schizophrenia admitted to the hospital from February 2020 to March 2022 were selected as the research objects and divided into two groups according to random number table method.The control group(n=37)was treated with medication,and the observation group(n=37)was treated with repetitive transcranial magnetic stimulation on the basis of control group.The clinical efficacy,cognitive function and sleep quality of the two groups were compared.Results The total clinical effective rate of the observation group was 94.59%,which was higher than 78.38%of the control group,and the difference was statistically significant(P<0.05).After treatment,the minimental state examination score of the observation group was(22.40±3.48)points,which was higher than(18.25±3.30)points of the control group,and the difference was statistically significant(P<0.05).After treatment,the scores of sleep onset time,sleep duration,sleep efficiency,sleep quality,sleep disorders,hypnotic drugs,and daytime dysfunction of Pittsburgh sleep quality index in the observation group were(1.33±0.07)points,(1.24±0.10)points,(0.80±0.08)points,(1.02±0.07)points,(1.02±0.05)points,(1.12±0.08)points and(1.12±0.15)points,respectively,which were lower than(1.62±0.10)points,(1.70±0.15)points,(1.12±0.10)points,(1.34±0.09)points,(1.33±0.07)points,(1.46±0.10)points and(1.60±0.18)points of the control group,and the differences between the groups were statistically significant(P<0.05).Conclusion Repetitive transcranial magnetic stimulation combined with drug therapy has a remarkable application effect in schizophrenia patients,which can effectively improve their cognitive function and improve their sleep quality.
作者
张荣荣
石娜
ZHANG Rongrong;SHI Na(No.5 Ward,Tai'an Psychiatric Hospital,Tai'an Shandong,271000,China;Health Examination Center,Tai'an Central Hospital,Tai'an Shandong,271000,China)
出处
《反射疗法与康复医学》
2022年第20期77-80,共4页
Reflexology And Rehabilitation Medicine
关键词
精神分裂症
重复经颅磁刺激
药物
认知功能
睡眠质量
临床疗效
Schizophrenia
Repetitive transcranial magnetic stimulation
Medication
Cognitive function
Sleep quality
Clinical efficacy
