摘要
目的:探讨益母草干品、 酒益母草、 醋益母草以及四制益母草质量,为制定四制益母草质量标准提供数据支持.方法:按照 《中国药典(2015年版)》 对益母草不同炮制品进行水分、 总灰分、 二氧化硫及浸出物含量测定;以盐酸水苏碱和盐酸益母草碱作为评价指标,采用高效液相色谱法进行含量测定.结果:益母草不同炮制品水分含量范围为10.9%-11.9%;总灰分含量范围为6.8%-7.9%;二氧化硫未有检出;浸出物含量范围为16.3%-17.8%;盐酸水苏碱含量范围为0.57%-0.68%;盐酸益母草碱含量范围为0.181%-0.194%.结论:益母草不同炮制品水分、 总灰分、 浸出物及二氧化硫残留均符合药典规定;干益母草盐酸水苏碱、 盐酸益母草碱含量最高,四制益母草含量最低,其药理、 毒理物质基础有待进一步研究.
Objective To study the quality of dried Leonurus heterophyllus, liquor Leonurus heterophyllus, vinegar Leonurus heterophyllus and Sizhi Leonurus heterophyllus. And provide data support for formulating quality standards of Sizhi heterophyllus. Method According to the Chinese Pharmacopoeia(2015 edition), determine the contents of water, total ash, sulfur dioxide and extracts in different processed products of Leonurus heterophyllus. And determine the contents of stachydrine hydrochloride and leonurnine hydrochloride by high performance liquid chromatography. Result The moisture content ranged from 10.9% to 11.9%, total ash content ranged from 6.8% to 7.9%, sulfur dioxide was not detected, extract content ranged from 16.3% to 17.8%, stachydrine hydrochloride content ranged from 0.57% to 0.68%, and Leonurus hydrochloride content ranged from 0.181% to 0.194%. Conclusion The contents of moisture, total ash, extracts and sulfur dioxide residues in different processed products of Leonurus heterophyllus were in accordance with the provisions of pharmacopoeia. The contents of stachydrine hydrochloride and Leonurus hydrochloride in dried Leonurus heterophyllus were the highest and those in Sizhi heterophyllus were the lowest. Those pharmacological and toxicological substances need to be further studied.
作者
翁志平
梁锦杰
WENG Zhiping;LIANG Jinjie(Guangdong Xinxing Chinese Medicine School,Yunfu 527400,China)
出处
《中国民族民间医药》
2019年第11期31-34,共4页
Chinese Journal of Ethnomedicine and Ethnopharmacy
基金
广东省中医药局科研项目《新兴县传统中药炮制成品四制艾叶、益母草质量标准研究》(20191410)
关键词
益母草
炮制品
四制益母草
质量研究
Leonurus Heterophyllus
Processed Products
Sizhi Heterophyllus
Quality Research
