摘要
目的:探讨加味枸橘汤治疗慢性附睾炎的临床疗效。方法选择确诊的慢性附睾炎患者80例,随机分成对照组(35例)和治疗组(45例)。对照组口服左氧氟沙星,2次/d,0.2g/次,治疗组口服中药加味枸橘汤治疗。两组分别在治疗前和治疗后4w检测慢性附睾炎症状指数评分(CESI)疼痛评分、生活质量评分、CESI总分,并统计其临床效率。结果80例患者顺利完成试验,对照组治疗后CESI疼痛评分、生活质量评分、CESI总分均有下降趋势,CESI总分较治疗前有统计学差异(P<0.05);治疗组的各项指标治疗后也显著下降(P<0.05),并且优于对照组(P<0.05),治疗组的显效率和总有效率均优于对照组(P<0.05)。结论加味枸橘汤治疗慢性附睾炎的临床疗效显著,值得临床推广应用。
Objective:To investigate the curative ef ect of Jiaweigoujutang decoction in the treatment of chronic epididymitis.Methods:Selecte 80cases of diagnosed chronic epididymitis,and randomly assigned them to control group(35 cases)and the treatment group(45 cases).The control group received levofloxacin treatment(0.2g,bid),while the treatment group taking Traditional Chinese Medicine Jiaweigoujutang decoction.Before and after the treatment of 4 weeks,we detected the pain scores of Chronic Epididymitis Symptom Index(CESI),quality of life scores,CESI total scores,and calculate the ef iciency.Results:80 patients successful y completed the study.In the control group,it was decreased of pain scores of CESI,quality of life scores,CESI total scores,CESI total scores had a statistics dif erence compared to pre-treatment(P<0.05).In the treatment group,al indicatrix was obviously decreased compared to pre-treatment(P<0.05).And the reduced margin is bet er than the control group(P<0.05).Besides,the excellence rate total ef iciency of the treatment group is bet er than the control group(P<0.05).Conclusion:The Traditional Chinese Medicine Jiaweigoujutang shows significant ef icacy on chronic epididymitis,which is worthy of clinical application.
作者
刘栋赟
孙大林
金保方
张新东
夏国守
LIU Dong-yun;SUN Da-lin;JIN Bao-fang;ZHANG Xin-dong;XIA Guo-shou(Nanjing University of Traditional Chinese Medicine Research Institute of Andrology,Nanjing,Jiangsu 210023,China;Nanjing University of Traditional Chinese Medicine the Third Affiliated Hospital,Nanjing,Jiangsu 210001,China)
基金
国家自然科学基金(81273760/H2709)
国家'973'国家重点基础研究发展计划课题(编号2010CB530401).
