摘要
目的探讨二维超声联合容积对比成像和磁共振成像(MRI)对胎儿胼胝体发育异常的诊断价值。方法收集超声检查可疑胎儿胼胝体发育异常后于1周内行MRI检查并获得新生儿期明确诊断的73例胎儿为研究对象。二维超声观察胎儿头颅各个切面获得间接征象,三维探头以胎儿头颅横切面丘脑平面作为容积对比成像取样初始A-平面,在超声仪器上获得对应的C-平面观察胼胝体。MRI扫描获得胎儿横断位、冠状位、矢状位图像,观察透明隔腔、侧脑室、第三脑室及胼胝体等。分析二维超声联合容积对比成像和MRI的诊断结果及灵敏度。结果新生儿影像学检查结果显示73例胎儿中部分型胼胝体缺如32例,胝体发育不良29例,胼胝体发育正常12例。二维超声联合容积对比成像和MRI对部分型胼胝体缺如的诊断结果和灵敏度差异没有统计学意义(均P>0.05),对胼胝体发育不良的诊断结果和灵敏度差异有统计学意义(P<0.05)。结论二维超声联合容积对比成像和MRI对诊断部分型胼胝体缺如均具有较高价值,但MRI对诊断胼胝体发育不良更有优势,MRI可以作为超声的有益补充和验证手段,为临床提供更为精准的诊断。
Objective To investigate the diagnostic value of two-dimensional ultrasound combined with volumetric contrast imaging(VCI)and magnetic resonance imaging(MRI)for the developmental abnormalities of the fetal corpus callosum.Methods Seventy-three fetuses who underwent cranial MRI within 1 week after suspected fetal corpus callosum dysplasia on ultrasound and received a definitive diagnosis in the neonatal period were retrospectively recruited for the study.The fetal corpus callosum was observed in the transverse,coronal,and sagittal views of the fetus,and the hyaline septal cavity,lateral ventricle,third ventricle,and corpus callosum were observed in the MRI scan.The diagnostic results and sensitivity of two-dimensional ultrasound combined with volumetric contrast imaging and MRI were analyzed.Results Neonatal imaging showed that among 73 fetuses,32 had agenesis of the corpus callosum,29 had hypoplasia of the corpus callosum,and 12 had normal development of the corpus callosum.The differences in diagnostic results and sensitivity between 2D ultrasound combined with volumetric contrast imaging and MRI testing for agenesis of the corpus callosum were not statistically significant(all P>0.05),and the differences in diagnostic results and sensitivity for hypoplasia of the corpus callosum were statistically significant(P<0.05).Conclusions Both 2D ultrasound combined with volumetric contrast imaging and MRI are of high value for the diagnosis of partial-type agenesis of the corpus callosum,but MRI is more advantageous for the diagnosis of agenesis of the corpus callosum,and MRI can be a useful supplement and verification tool for ultrasound to provide a more accurate clinical diagnosis.
作者
孔德璇
何晓燕
李慧东
张志坤
Kong Dexuan;He Xiaoyan;Li Huidong;Zhang Zhikun(Department of Ultrasound,Tianjin Central Hospital of Obstetrics and Gynecology,Clinical School of Obstetrics and Gynecology,Tianjin Medical University,Nankai University Maternity Hospital,Tianjin 300052,China;Department of Radiology,Tianjin Central Hospital of Obstetrics and Gynecology,Clinical School of Obstetrics and Gynecology,Tianjin Medical University,Nankai University Maternity Hospital,Tianjin 300052,China)
出处
《国际生物医学工程杂志》
CAS
2022年第5期414-418,共5页
International Journal of Biomedical Engineering
关键词
二维超声
容积对比成像
磁共振成像
胼胝体发育异常
Two-dimensional ultrasound
Volumetric contrast imaging
Magnetic resonance imaging
Agenesis of the corpus callosum
