摘要
目的探讨鼻内镜下改良高选择性翼管神经低温等离子消融术对中重度变应性鼻炎的临床疗效。方法选择2017年1月—2019年1月在徐州医科大学附属淮安医院耳鼻咽喉头颈外科就诊并确诊为中重度变应性鼻炎的88例患者为研究对象,其中男46例,女43例,年龄(48.74±1.26)岁,病程(6.65±0.64)年。将接受规范化药物治疗的46例患者作为对照组,接受鼻内镜下改良高选择性翼管神经低温等离子消融术治疗的42例患者作为观察组。在治疗前、治疗后对所有患者行鼻结膜炎生存质量(RQLQ)评分评估,并统计分析治疗前、治疗后的两组临床症状积分及并发症(眼干、鼻腔干燥、上腭麻木、鼻出血)的发生率。结果研究组治疗后6个月、1年、3年的RQLQ评分(0.96±0.55、1.13±0.52、1.26±0.51)均低于对照组(1.87±0.46、1.98±0.61、2.01±0.55),差异均有统计学意义(均P<0.05)。治疗后研究组打喷嚏、流鼻涕和鼻肿胀等临床症状积分均低于对照组(1.03±0.24比1.58±0.50、0.86±0.25比1.33±0.41、0.59±0.18比0.88±0.23),差异均有统计学意义(均P<0.05)。两组在眼干、鼻腔干燥、上腭麻木、鼻出血等方面差异均无统计学意义(均P>0.05)。结论鼻内镜下高选择性翼管神经阻滞术对中重度变应性鼻炎的效果优于单纯药物治疗,可显著减轻临床症状,改善患者生活质量。
Objective To evaluate the clinical effects of modified highly selective pterygoid canal nerve block by low temperature radiofrequency ablation under nasal endoscopy in patients with moderate to severe chronic rhinitis.Methods A total of 88 patients who were diagnosed with moderate and severe allergic rhinitis at the Department of Otorhinolaryngology,Head and Neck Surgery,Huai'an Hospital,Xuzhou Medical University from January 2017 to January 2019 were selected as the subjects,including 46 males and 43 females,with a mean age of(48.74±1.26)years.The disease course was(6.65±0.64)years.Forty-six patients who received standardized drug treatment were included in a control group,and 42 patients who received modified highly selective pterygoid canal nerve block by low temperature radiofrequency ablation under nasal endoscopy treatment were included in an observation group.The quality of life(QoL)score of rhinoconjunctivitis was evaluated before and after treatment,and the clinical symptom scores and the incidence of complications(dry eyes,dry nose,numbness of palate,and epistaxis)were statistically analyzed.Results The QoL scores of the study group at 6 months,1 year,and 3 years after treatment(0.96±0.55,1.13±052,and 1.26±0.51,respectively)were all lower than those in the control group(1.87±0.46,1.98±0.61,and 2.01±0.55,respectively)(P<0.05 for all).After treatment,the scores of clinical symptoms of sneezing,runny nose,and nasal swelling in the study group were all significantly lower than those in the control group(1.03±0.24 vs 1.58±0.50,0.86±0.25 vs 1.33±0.41,and 0.59±0.18 vs 0.88±0.23,respectively;P<0.05 for all).There was no significant difference between the two groups in dry eyes,dry nasal cavity,numbness of the palate,and epistaxis(P>0.05 for all).Conclusion The clincial effects of modified highly selective pterygoid canal nerve block by low temperature radiofrequency ablation under nasal endoscopy for patients with moderate to severe chronic rhinitis is better than that of drug therapy alone,which can significantly reduce clinical symptoms and improve the quality of life of patients.
作者
戴俊
李硕
曹影
汪守峰
宋红毛
蔡菁菁
邵敏
陈莉
程雷
怀德
Dai Jun;Li Shuo;Cao Ying;Wang Shoufeng;Song Hongmao;Cai Jingjing;Shao Min;Chen Li;Cheng Lei;Huai De(Department of Otorhinolaryngology,Head and Neck Surgery,Xuzhou Medical University Affiliated Huaian Hospital,Huaian 223002,China;Department of Otorhinolaryngology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)
出处
《中华临床医师杂志（电子版）》
CAS
北大核心
2023年第6期689-693,共5页
Chinese Journal of Clinicians(Electronic Edition)
基金
江苏省卫生计生委科研课题(H2017012)
