摘要
目的探讨立体定向放射治疗肝脏恶性肿瘤的临床疗效。方法利用大恒公司star-1000X线立体定向放射治疗计划系统制定放疗方案,共治疗57例肝脏恶性肿瘤患者。等剂量曲线80%~90%包绕临床靶体积,总剂量28.8~40.0Gy,中位剂量36Gy。分割处方剂量4.8~8Gy,每周2~3次,共4~6次。结果无1例患者在治疗过程中死亡,只有1例患者因乙型肝炎急性发作中断治疗。有效率(RR)完全缓解(CR)+部分缓解(PR)75.4%,CR15例,PR28例,稳定(SD)11例,进展(PD)3例。1年生存率为68.4%,2年生存率为40.3%,3年生存率为10.5%。结论立体定向放射治疗肝脏恶性肿瘤安全且有较好疗效,能延长肝脏恶性肿瘤患者的生命。
Objective To investigate the clinical efficacy of stereotactic radiotherapy for liver malignant tumor.Methods 57 patients with liver malignant tumor were treated with Daheng star-1000 X-knife stereotactic therapentic system. 80%~90% isodosage curve enclose the clinical target volume, the total dose was 28.8Gy^40Gy, with median dose being 36Gy. The fractional doses was 4.8Gy～8Gy, 2～3 times per week, 4~6 fractions in total.Results No patient died during treatment. Only one patient stopped treatment for hepatitis B acute exacerbation. The response rate CR+PR)was 75.4%, complete remission(CR) 15cases,partial remission (PR) 28cases,SD 11cases,PD 3cases; 1-year, 2-year and 3-year survival rates were 68.4%,40.3%and 10.5%, respectively.Conclusion Stereotactic radiotherapy is a safe and effective treatment method for liver malignant tumor, with survival benefit.
出处
《临床和实验医学杂志》
2006年第9期1309-1310,共2页
Journal of Clinical and Experimental Medicine
关键词
肝脏肿瘤
立体定向
放射治疗
Liver malignant tumor
Stereotactic
Radiotherapy
