摘要
目的了解戊型肝炎有无慢性化趋势及其程度。方法对我国新疆南部某乡1986年1月暴发流行的戊型肝炎病人106例进行临床回顾、现症、实验室、B超等方面的调查。结果106例戊肝病人中有48例(45.28%)不同程度反复出现消化症状有36例(33.96%)有明显的右侧肋下压痛、蜘蛛痣、及及腹壁静脉曲张体征;血清免疫标记物检测:HEVIgM阳性1例(0.94%)、HEVIgG阳性55例(51.89%)、HBsAg阳性5例(4.72);血清丙氨转氨轻度生高14例(13.21%)、A/G比例改变41例(38.68%);B超声像图肝胆改变36例(48脏/次)(33.96%)。符合慢性肝炎诊断的41例(38.68%)。结论戊型肝炎病后51.89%抗HEVIgG可持续阳性,至少18年以上。在流行病学上有较大的意义。有38.68%(41/106)成为慢性肝炎,大部分为慢性迁延型。未见肝硬化。
Objective To underatand that pentahepatitis have chronic tendency or havent and degree of it.Methods To vestigate the 106 cases of patients witln pentahepatitis that happened in some village of south of Xing Jiang Province of china in august 1985 to february 1988 on clinical present symptoms and review and detection of laboratory and examination of ultrasonic B.Results The 48cases (45.28%) of 106 cases of patients with pentahepatitis appear repeatedly symptoms from peptic system on different degree.The 36 cases of them appear apparent tenderness under right rib and spider angioma and sign of phlcbcuryxnla of abdominal wall.Their detection of label of serum immunity are,One case is positive HEV IgG(0.94%). and 55 cases are positive HEVIgG (51.89%).and 5 cases are positive Hbsag(4.72%).Glutamic-pyrumic! transaminase of 14 cases are to rise sligntly (13.21%).Proportion of A/G of / 41cases are to change(38.68%).36 cases have Image-change of ultrasonic B of liver and gallbladder (33.96%). 41 cases accord with diagnostic standard of chronic hepatitis.Conclusion Anti-HEVIgG of the patients after pentahepatitis are positive constantly to make up 51.89 per cent of the total patients. At least it may maintain for eighteen years and some may exist througn one's life. It have considerable significance on epidemiology. 38.68 per cent patients with posititve Anti-HEVlgG may become patients with chronic hepatitis. The great part of them becorne chronic delayed hepatitis but dont discover the patients with hepatocirrhosis among them.
出处
《中国实用医药》
2006年第3期21-23,共3页
China Practical Medicine
关键词
戊型肝炎
慢性化
Pentahepatitis (Hepatitis-E)
chronic tendency.
