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动脉粥样硬化发生的免疫学机制 被引量：10

Regulation of immune mechanisms in atherosclerosis
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摘要 在动脉粥样硬化形成发展中,有大量与免疫相关的细胞参与并形成了一系列免疫反应机制,主要包括:免疫系统的单核,巨噬细胞和淋巴细胞、内皮细胞、平滑肌细胞等,它们在各种免疫分子的协调下相互作用,相互影响,共同参与了动脉粥样硬化的发生、发展。 In the development of atherosclerosis, many immune-related cells, such as macrophages, lymphocytes and endotheliocytes, and smooth muscle cells, are involved and form a serial of mechanisms of immunologic reactions. They are interacted through the regulation of immunologic molecules and contribute to the pathogenesis of atherosclerosis.
作者 陈文娜 李曦明
机构地区 辽宁中医学院研究生部
出处 《免疫学杂志》 CAS CSCD 北大核心 2004年第z1期109-111,共3页 Immunological Journal
关键词 动脉粥样硬化 自身免疫 慢性炎症 免疫分子 <Keyword>herosclerosis Autoimmunity Chronic inflammation Immunologic molecule
分类号 R543.5 [医药卫生—心血管疾病]
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参考文献16

  • 1[1]Glass CK, Witztum JL. Atherosclerosis: the road ahead [ J].Cell, 2001, 104(4): 503 - 516
  • 2[2]Deocnfeld Y, Sherer Y, Harats D. Atherosclerosis as an infections,inflammatory and antoimmune disease [ J]. Trends immunol, 2001,22(6) :293 - 295
  • 3[3]Salonen JT, Yla-Herttuala S, Yamamoto R et al. Autoantibody against oxidised LDL and progression of carotid atherosclerosis [J]. Lancet, 1992,339(8 798) :883 - 887
  • 4[4]Witzutm JL. Immunological response to oxidized LDL [ J] .Atherosclerosis, 1997,131 (suppl) :S9 - S11.
  • 5[5]Cominacini L, Pasini AF, Garbin U, et al. Oxidized lowdensity lipoprotein (Ox-LDL) binding to Ox-LDL receptor-1in endothelial cells induces the activation of NF- кB through an increased production of intracellular reactive oxygen species [J]. J Biol Chem, 2000, 275(17): 12 633.
  • 6雷新军,马爱群,任冰稳,耿涛,张葳.OxLDL直接诱导人外周血单核细胞表达致炎细胞因子mRNA[J].中国免疫学杂志,2004,20(2):93-96. 被引量：4
  • 7[7]Leinonen M , Saikku P. Interaction of Chlamydia pneumoniae infection with other risk factors of atherosclerosis [J]. Am Heart J, 1999 ,138(5 Pt 2):S504- S506.
  • 8[8]Ponzetto A, La Rovere MT, Sanseverino P, et al. Association of Helicobacter pylori infection with coronary heart disease.Study confirms previous findings [J] . Br Med J, 1996,312(7 025) :251 - 257.
  • 9[10]Jaffe EA,Minick CR,Adelman B, et al. Synthsis of basement collagen by cultured Human endothelial cells[ J] .J Exp Med,1991,144(1) :209 - 225.
  • 10[11]Stemme S,Faber B, Holm J, et al. T lymphocytes from human atherosclerotic plaques recognize oxidized LDL[J]. Proc Natl Acad Sci USA,1995,92(9): 3 893-3 897.

二级参考文献13

  • 1[1]Jaber J, Murin J, Kinova S et al.The role of infection and inflammation in the pathogensis of atherosclerosis[J]. Vnitr Lek, 2002;48(7):657-666.
  • 2[2]Hakkinen T, Karkola K, Yla-Herttuala S. Macrophages, smooth muscle cells, endothelial cells, and T-cells expression CD40 and CD40L in fatty streaks and more advanced human atherosclerotic lesions. Colocalization with epitopes of oxidized low-density lipoprotein, scavenger receptor, and CD16(Fc gamma RⅢ)[J]. Virchows Arch, 2000;437(4):396-405.
  • 3[3]Hirano K, Yamashita S, Nakagawa Y et al. Expression of human scavenger receptor class B type I in cultured human monocyte-derived macrophages and atherosclerotic lesions[J]. Circ Res, 1999;85(1):108-116.
  • 4[4]Ares M P, Bengt K, Per E et al. Oxidized LDL induces transcription factor activator protein-1 but inhibits activation of nucler factor-κB in human vascular smooth muscle cells[J]. Arterioscler Thromb Vasc Biol,1995;15(10):1584-1590.
  • 5[5]Frosteg Ard J, Uifgren AK, Nyberg P et al. Cytokine expression in advanced human atherosclerotic plaques:dominance of pro-inflammatory (Th1)and macrophage-stimulating cytokines[J]. Atherosclerosis, 1999;145(1):33-34.
  • 6[6]Van Berkel T J, Van Eck I, Herijgers N et al. Scavenger receptor class A and B,their role in atherogenesis and the matabolism of modified LDLand HDL[J]. Ann N Y Acad Sci, 2000;902(5):113-126.
  • 7[7]Aiello R J, Bourassa P A, Lindsey S et al. Monocyte chemoattractant protein-1 accelerates atherosclerosis in apolipoprotein E-degicient mice[J]. Arterioscler Thromb Vasc Biol, 1999;19(6):1518-1525.
  • 8[8]Kim H H, Ha Hj, Kim S O et al. KR31372, a benzopyran derivative, inhibits oxidized LDL-stimulated proliferation and migration of vascular smooth muscle cells[J]. Fundam Clin Pharmacol, 2000;14(5):469- 476.
  • 9[9]Cucina A, Pagliei S, Borrelli V et al. Oxidized LDL(OxLDL)induces production of platelet derived growth factor AA(PDGF AA)from aortic smooth muscle cells[J]. Eur J Vasc Endovasc Surg,1998;16(3):197-202.
  • 10[10]Pinderski,Oslund L J, Hedrick C C et al. Interleukin-10 blocks atherosclerotic events in vitro and in vivo [see comments] [J]. Arterioscler Thromb Vasc Biol, 1999;19(12):2847-2853.

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免疫学杂志
2004年 第z1期

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