摘要
以水杨醛和乙酸酐为原料,无水氟化钾为催化剂,在微波辐射下合成香豆素,当水杨醛:乙酸酐:氟化钾=0.1:0.32:0.18时,采用480W微波辐射10 min。香豆素产率可达91％以上,较传统方法有反应时间短、产率高的特点。
The synthesis of coumarin is performed by salicylal and acetic anhydride under microwave irradiation and the reaction is catalysised by dry potassium fluoride. The optimum reaction conditions are as follows; 0. 1 mol salicylal, 0. 32 mol acetic anhydride, 0. 18 mol dry potassium fluoride, 480 W microwave power and 10 min microwave irradiaition. The yield of coumarin reachs 91%. Comparised with habitual method, the time is shorter and the yield is higher through this method.
出处
《化学与生物工程》
CAS
2003年第z2期27-27,36,共2页
Chemistry & Bioengineering
关键词
香豆素
微波辐射
合成
coumarin
microwave irradiation
synthesis
