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NSE和CYFRA21-1联合检测对肺癌的诊断价值 被引量:1

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摘要 目的:探讨肺癌患者血清神经元烯醇化酶(NSE)和非小细胞肺癌相关抗原(CYFRA21-1)的临床价值。方法:采用电化学发光法检测182例肺癌患者、102例肺良性病变和106例正常对照组的血清NSE和CYFRA21-1水平。结果:肺癌患者血清NSE和CYFRA21-1水平显著性高于肺癌良性疾病患者和正常对照组(P<0.01),小细胞肺癌血清NSE水平为最高,鳞状细胞癌,腺癌患者血清CYFRA21-1水平显著性增高。NSE和CYFRA21-1水平随分期升高而增高。结论:NSE和CYFRA21-1可作为有效的肺癌肿瘤标志物。
作者 王红
机构地区 长治市人民医院
出处 《实用医技杂志》 2008年第28期3878-,共1页 Journal of Practical Medical Techniques
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  • 1刘智鑫,刘国津.人非小细胞肺癌细胞药物敏感性检测及其与耐药因子p53抗体和GST-π表达的关系[J].吉林大学学报(医学版),2005,31(5):795-798. 被引量:9
  • 2[1]Arrigoni MG, Woolner LB, Bernatz PE. Atypical carcinoid tumors of the lung. J Thorac Cardiovasc Surg,1972,64(3):413-421.
  • 3[2]Carnaghi C, Rimassa L, Garassino I, et al. Clinical significance of neuroendocrine phenotype in non-small-cell lung cancer. Ann Oncol,2001,12 Suppl 2:S119-123.
  • 4[3]Yesner R. Heterogeneity of so-called neuroendocrine lung tumors. Exp Mol Pathol,2001,70(3):179-182.
  • 5[5]Onuki N, Wistuba II, Travis WD, et al. Genetic changes in the spectrum of neuroendocrine lung tumors. Cancer,1999,85(3):600-607.
  • 6[6]Travis WD, Rush W, Flieder DB, et al. Survival analysis of 200 pulmonary neuroendocrine tumors with clarification of criteria for atypical carcinoid and its separation from typical carcinoid. Am J Surg Pathol,1998,22(8):934-944.
  • 7[8]Schleusener JT, Tazelaar HD, Jung SH, et al. Neuroendocrine differentiation is an independent prognostic factor in chemotherapy-treated nonsmall cell lung carcinoma. Cancer,1996,77(7):1284-1291.
  • 8KT,Tsai GM,Chiou YC,et al.IL-6 induces neuroendocrine dedifferentiation and cell proliferation in non-small cell lung cancer cells[J].Am J Physiol Lung Cell Mol Physiol,2005,289:L446-L453.
  • 9Battafarano RJ,Fernandez FG,Ritter J,et al.Large cell neuroendocrine carcinoma:An aggressive form of non-small cell lung cancer[J].Thorac Cardiovasc Surg,2005,130:166-172.
  • 10Ruibal A,Nunez MI,Rodriguez J,et al.Cytosolic levels of neuron-specific enolase in squamous cell carcinomas of the lung[J].Biol Markers,2003,18(3):188-194.

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