摘要
目的探讨抗生素相关性肠炎(AAC)临床特点及治疗方法,提高诊治水平。方法将本院2006年1月至2007年12月收治的57例抗生素相关性肠炎患者随机分成两组,对照组28例,给予口服甲硝哇、蒙脱石散;治疗组29例,给予甲硝唑、蒙脱石散、乳酸菌素片保留灌肠,同时加用丽珠肠乐。结果对照组有效率67.9%,治疗组有效率89.7%。两组间相比较差异有统计学意义(P<0.05)。结论改变甲硝唑传统给药方式,针对AAC的发病机制,采用综合性治疗手段可提高疗效,减少不良反应的发生率。
Objective To explore the clinical characteristics and therapeutics of antibiotic-associated colitis (AAC),and to im- prove its diagnosis and treatment.Methods 57 patients with AAC from Jan 2006 to Dec 2007 in our hospital were enrolled in the investigation.All subjects were randomly divided into control group (n=28,given peroral administration of metronidazole and montmorillonite powder) and treatment group (n=29,given retention enema of metronidazole,montmoriUonite powder and lacto- lin tablets;besides,bifidobiogen-livzon was given).Results The effective rate in treatment group (89.7%) was remarkably higher than that in control group (67.9%).The difference was statistically significant (P<0.05).Conclusion The alteration of the con- ventional route of metronidazole administration and application of comprehensive therapeutic tool aiming directly at the pathogenesy of ACC contribute to improvement of therapeutic effect and decrease of incidence of adverse effects.
出处
《中国医药指南》
2008年第16期25-26,共2页
Guide of China Medicine
关键词
抗生素相关性肠炎
感染
腹泻
治疗
antibiotic-associated colitis
infection
diarrhea
treatment
