糖尿病前期患者大血管病变的超声研究被引量：8

Ultrasound study of the macro-vascular disesase in pre-diabete patients

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摘要目的:通过超声检查糖尿病前期(葡萄糖耐量低减IGT和空腹血糖调节受损IFG)患者的大动脉声像图表现情况及血管内皮舒张功能,探讨该期患者大血管的损害程度。方法:选择经临床诊断为IGT、IFG患者55例,同时选择健康人群30例作为对照。采用超声检查颈动脉、股动脉内膜-中层厚度及斑块情况,然后测定肱动脉内皮依赖性(EDV)和非内皮依赖性舒张功能。结果:糖尿病前期组颈动脉及股动脉内中膜厚度较对照组均显著增厚,回声不均匀。糖尿病前期患者颈动脉和股动脉动脉粥样硬化斑块发生率(33%)高于正常对照组(16%)。糖尿病前期各组EDV均较正常对照组降低,而IFG伴IGT组又较IFG组和IGT组减低。硝酸甘油介导的血管扩张在各组间无显著差异性。结论:糖尿病前期患者即有动脉粥样硬化的表现,并存在着血管内皮舒张功能障碍,而同时有IGT和IFG的患者血管内皮舒张功能损害更重。 Objective To investigate the ultrasonographic imaging and endothelial dilation function(EDF)of macrovascular in pre-diabetes patients(include impaired glucose tolerance IGT and impaired fasting glucose IFG)via ultrasonography.And try to assess the degree of damage on macrovascular in pre-diabetes patients.Methods :In this study,55 patients with IGT 、 IFG and 30 normal subjects were recruited.Using high resolution ultrasound,the intima-media thickness(IMT)and atherosclerotic plaque of carotid and femoral art...

作者邹荣莉沈亚梅邱英武刘莉高燕华

机构地区陕西省人民医院超声科

出处《陕西医学杂志》 CAS 北大核心 2008年第11期1493-1495,共3页 Shaanxi Medical Journal

基金陕西省科技计划社会发展攻关科研课题(2004K16-G2)

关键词糖尿病/病理生理学 @葡萄糖耐量低减动脉硬化/并发症超声捡查 Diabetes/physiopathology @Impaired glucose tolerance Arteriosclerosis/etiology Ultrasonography

分类号 R587.1 [医药卫生—内分泌]

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