摘要
目的:探讨大蒜素注射液雾化吸入辅助治疗慢性支气管炎急性发作患者的效果与机制。方法:将116例慢性支气管炎患者随机分成治疗组64例和对照组52例,对照组运用西医常规治疗(抗感染,平喘及对症处理),治疗组在西医治疗基础上加用大蒜素注射液雾化吸入治疗。观察两组的治疗总有效率,并检测所有病例治疗前后氧分压、二氧化碳分压、血清TNF-α和IFN-γ含量(ELISA法检测)。结果:治疗组总有效率为93.75%,对照组总有效率为67.31%,两组疗效比较差异有统计学意义(P<0.05),治疗组优于对照组。两组的氧分压、二氧化碳分压及外周血TNF-α、IFN-γ含量比较均有统计学差异,治疗组优于对照组。结论:大蒜素注射液雾化吸入配合西医常规治疗可以有效改善慢性支气管炎患者急性发作期症状并缩短病程。
AIM: To evaluate the efficacy of inhaling atomized garlicin injection for assistant treating acute exacerbations of chronic bronchitis.METHODS: Based on the conventional treatment,64 cases in the treatment group were given inhaled atomized garlicin injection,while other 52 cases in the control group were treated by the conventional treatment.Total effective rates of two groups were observed,the oxygen partial pressure,carbon dioxide partial pressure,the TNF-α and IFN-γ of blood serum in all cases were detec...
出处
《中国临床药理学与治疗学》
CAS
CSCD
2008年第9期1058-1061,共4页
Chinese Journal of Clinical Pharmacology and Therapeutics
关键词
慢性支气管炎
急性发作
大蒜素注射液
雾化吸入
chronic bronchitis
acute exacerbations
garlicin injection
inhaled atomized
