摘要
血液透析滤过(hemodiafiltration,HDF)结合了血液透析(hemodialysis,HD)和血液滤过(hemofiltration,HF)的特点,可以有效地清除血液中中小分子毒素,减轻炎性反应状态,维持透析中血流动力学稳定,改善终末期肾脏病患者贫血、钙磷代谢紊乱、营养状态等症状。近年来大型的观察性研究显示HDF可以降低终末期肾脏病患者的死亡风险。本文综述了HDF在维持性透析患者中的临床应用及近期进行的大型观察性或随机对照试验的结果。
Hemodiafiltration(HDF)is an extracorporeal renal-replacement technique using a highly permeable membrane,in which diffusion and convection are combined to enhance solute removal in a wide spectrum of molecular weights.HDF can improve clinical conditions and reduce morbidity compared with conventional hemodialysis.In this review,it summarizes recent views about clinical aspects of HDF,the main observational studies and ongoing randomized-controlled trials.
出处
《首都医科大学学报》
CAS
北大核心
2009年第2期154-160,共7页
Journal of Capital Medical University
