摘要
目的探讨帕金森病(parkinson′s disease,PD)患者血尿酸水平变化。方法选择2007年1月—2008年3月于襄樊市第一人民医院门诊和病房就诊的93例PD患者为病例组,选择年龄、性别、民族与PD患者相匹配的健康人91例为对照组。检测两组受检者的血尿酸水平,并进行比较。结果病例组血尿酸水平为(270±75)μmol/L,对照组为(342±62)μmol/L,两组血尿酸水平间差异有统计学意义(t=7.09,P<0.01);病例组低尿酸患者43例,对照组14例,两组低尿酸的发生率间差异有统计学意义(χ2=20.48,P<0.01)。结论PD患者的血尿酸水平低于正常对照者。尿酸作为神经系统中的一种重要抗氧化物,可能在PD的发生、发展中具有一定意义。
Objective To investigate the changes of serum uric acid content in patients with Parkinson s disease.Methods Totally 93 patients with Parkinson s disease receiving medical service in the First People s Hospital of Xiangfan City from Junuary 2007 to March 2008 were chosen as trial group,and 91 healthy persons whose age,sex and nationality matched the patients were erolled as the controls.The serum uric acid contents in the two groups were examined and compared.Results The serum uric acid was(270±75)μmol/L in...
出处
《中国全科医学》
CAS
CSCD
北大核心
2009年第7期595-596,共2页
Chinese General Practice
关键词
帕金森病
尿酸
活性氧
Parkinson disease
Uric acid
Reactive oxygen species
