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肝肾综合征的诊治

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摘要   1 概论  肝肾综合征(hepatorena syndrome,HRS),又称功能性肾衰竭(functional renal failure,FRF),是慢性肝病患者出现进展性肝功能衰竭和门脉高压时,以肾功能损伤、肾血流灌注减少和内源性血管活性系统异常为特征的一种综合征(1996年国际腹水研究小组推荐)[1],常伴有难治性腹水.它的特点是在肾内表现为肾血管显著收缩导致的肾小球滤过率(glomerularfiltratio rate, GFR)降低,在肾外则表现为因动脉舒张占主导地位导致的总的体循环血管阻力和动脉压下降.该征出现后,病情发展较快,患者死亡率高达80%~100%[2],故预防及早期诊断、治疗是挽救病人生命提高生存质量的关键.……
作者 张立伟
出处 《中国中医药现代远程教育》 2009年第6期69-70,共2页 Chinese Medicine Modern Distance Education of China
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