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肺癌的靶向治疗 被引量:3

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摘要 近几年来,肺癌的分子靶向治疗取得了较大的进展,靶向治疗新药不断涌现,在临床试验或临床应用中取得较为满意的结果,其中最引人注目的有吉非替尼(Iressa,ZD1839,Gefitinib)、埃罗替尼(TarcevaOSI774,Erlotinib)、赫赛汀(HerceptinTrastuzumab,)、西妥昔单抗(IMC2C225Cetuximab,Erbitux)和Bevacizumab(Avastin)等。
作者 张东
出处 《中国药物应用与监测》 CAS 2006年第4期41-44,共4页 Chinese Journal of Drug Application and Monitoring
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参考文献22

  • 1[1]Ryan PD,Chabner BA.On receptor inhibitors and chemotherapy[J].Clin Cancer Res,2000,6 (12):4607.
  • 2[2]Fukuoka M,Yano S,Giaccone G,et al.Multi-institutional randomized phase Ⅱ trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer[J].J Clin Oncol,2003,21 (21):2237.
  • 3[3]LoRusso PM,Herbst RS,Rischin D,et al.Improvements in quality of life and disease-related symptoms in phase I trials of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in non small cell lung cancer and other solid tumors[J].Clin Cancer Res,2003,9 (6):2040.
  • 4[4]Giaccone G,Johnson DH,Manegold C,et al.A phase Ⅲclinical trial of ZD 1839 (Iressa)in combination with gemcitabine and cisplatin in chemotherapy-naive patients with advanced non-small-cell lung cancer(INTACT1)[J].Ann Oncol,2002,13:2.
  • 5[5]Johnson M,Herbst R,Giaccone G,et al.ZD1839 (Iressa)in combination with paclitaxel and carboplatin in chemotherapy.naive patients with advanced non-small-cell lung cancer(NSCLC):results from a phase Ⅲ clinical trail (INTACT2)[J].Ann Oncol,2002,13:127.
  • 6吴一龙,杨学宁,杨衿记,黄玉娟.中国的非小细胞肺癌Gefitinib分子靶向治疗[J].中国肺癌杂志,2004,7(4):318-320. 被引量:15
  • 7[7]Huang SF,Liu HP,Li LH,et al.High frequency of epidermal growth factor receptor mutations with complex patterns in non small cell lung cancers related to gefitinib responsiveness in Taiwan[J].Clin Cancer Res,2004,10(24):8195.
  • 8[8]Lynch TJ,Bell DW,Sordella R,et al.Activating mutations in the epidermal frowth factor receptor underlying responsiveness of non small cell lung cancer to gefitinib[J].N Engl J Med,2004,350(21):2129.
  • 9[9]Tokumo M,Toyooka S,Kiura K,et al.The relationship between epidermal growth factor receptor mutation and clinicopathologic features in non small cell lung cancer[J].Clin Cancer Res,2005,11 (3):1167.
  • 10[10]Inoue A,Saijo Y,Maemondo M,et al.Severe acute interstitial pneumonia and gefitinib[J].Lancet,2003,361 (9352):137.

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