摘要
瘦素是脂肪组织分泌的一种激素，在能量平衡与体脂稳定中起重要作用。 1994年，瘦素的发现激发了人们对肥胖机制的深入研究，同时，对其独特的减肥效应也曾寄予厚望。 6年后的今天，瘦素作为一种减肥药物，似尚有许多不足之处，但其广泛的生理效应却格外引人注目。本文在复习文献的基础上，试图对该激素的生物学意义重新作一个恰当的评价。
Leptin,a hormone secreted by adipose tissue,plays an important role in the energy balance and lipostasis of the body.The discovery of leptin,has triggered vast enthusiastic research on the mechanism of obesity.Six years past,as a weight－ reducing drug,leptin still has much to be improed,while its extended physiological effects have already attracted special attention.This article is trying,on reviewing the literature,to reconsider what we have learned about this new hormone and to appropriately reevaluate its biological significance and clinical implication.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
2001年第13期8-11,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
关键词
瘦素
肥胖
能量平衡
leptin
obesity
energy balance
