摘要
目的:探讨扩血管药物(瑞其丁)和缩血管药物(垂体后叶素)治疗咯血的临床效果。方法:42例咯血患者,其中中等量咯血26例,大咯血16例。无垂体后叶素应用禁忌及应用后无严重副作用者坚持给予垂体后叶素治疗(垂体后叶素组,27例),反之应用瑞其丁(瑞其丁组,15例)。前组先给予垂体后叶素5～10IU,缓慢静脉推注,后予以20IU加入500ml液体中维持滴注。后组给予瑞其丁20mg加入到500ml液体中,维持静脉滴注。两组中咳血量大者(>300ml/24h)均辅以止血合剂、立止血及云南白药等止血治疗。结果:垂体后叶素组显效率高于瑞其丁组(P<0.05),其副作用发生率高于瑞其丁组(P<0.05)。结论:垂体后叶素止血起效快,疗程相对较短,故其仍不失为最有效止血药。但由于副作用发生率高,并且禁忌症较多,使其不能更广泛应用。而瑞其丁虽止血起效较慢,疗程相对延长,但其副作用较小,故在垂体后叶素应用受到限制时选择瑞其丁同样达到止血目的。
Objective To observe the effect of regitine and pituitrin in the therapeusis of the pulmonary hemoptysis.Methods42patients with pulmonary hemoptysis,among which were,26patients with average bleeding and 16patient with severe bleeding.Pituitrin was administrated for the patients with out contraindication and severe ill effect(26patients).At begining,5～10IU was veno -injected slowly,and then 20IUadded into 500ml liquid,ivgtt,to last.The remaining patients were given to regitine.20mg added into 500ml liquid,ivgtt,to last.In addition,hemosta sia mix-ture,reptilase and Yunnan white dru g were applied for the patients with s evere reptilase bleeding.Results The fre-quency of striking effect in group pi tuitrin was significantly higher th an that in group regitine(P∠0.05).The frequency of ill effect in group regitine was significantly lower than that in group pituitrin(P∠0.05).Conclusion Pituitrin can produce a fast effect for pulmonary h emoptysis and has a shorter course,s o it is an efficient hemostatic drug,but the ill effect is highter.However,regitin e has slower hemostasia effect and its course was relatively elongation,but the ill effect is lower.So it is very applica ble for the patients who have contraindication and ill effect of pituitrin.
出处
《安徽卫生职业技术学院学报》
2002年第2期24-25,共2页
Journal of Anhui Health Vocational & Technical College
关键词
咯血
保守治疗
垂体后叶素
瑞其丁
pulmonary hemoptysis
therapeusis conservative
pituitrin
regitine
