摘要
目的 对异丙酚联合麻醉用于人工流产手术的患者进行呼吸、循环系统及注射痛等方面的观察。方法 按美国麻醉医师协会 (ASA)分级标准Ⅰ～Ⅱ级 (Ⅰ级 :正常健康 ;Ⅱ级 :有轻度系统性疾病 ) 15 0例人工流产手术患者 ,随机分为四组 :A组 37例 ,单纯异丙酚麻醉 (2 0mg kg) ;B组 37例 ,在麻醉诱导前2min静脉给予阿托品 (0 0 1mg kg) ,而后复合异丙酚 ;C组 37例 ,麻醉诱导前不给予阿托品但静脉给芬太尼(1μg/kg) 而后复合异丙酚 ;D组 39例 ,在麻醉诱导前 2min静脉给予阿托品及芬太尼 ,而后复合异丙酚。分别记录病人手术时间、术中输液量、血氧饱和度、潮气量、血压、脉搏以及注射部位疼痛强度等变化 ,并进行统计学处理。结果 四组患者麻醉诱导后血压 ,脉搏均有不同程度的下降 ,A、C组注药后 2min、 4min与给药前比较差异有显著性 (P <0 0 1) ;A、B组病人的注射部位疼痛及对手术的反应变化得分分别明显大于C、D组(P <0 0 1) ;潮气量、血氧饱和度 (SPO2 )的一过性下降与给药前相比较差异显著 (P <0 0 1)。结论 资料表明D组病人在麻醉诱导前 2min静脉给于阿托品及芬太尼而后进行异丙酚复合静脉麻醉 ,辅以异丙酚静脉推注维持 ,能较好地满足无痛人工流产术的要求。
Objective To observe the effect of intravenous alliance anesthesia with propofol on breathe, circulatory system and pain releasing during operation of artificial abortion. Methods 150 ASA(American society of anesthesiologists)Ⅰ-Ⅱpatients undergoing artificial abortion were double-blindly divided into four groups:group A 37 cases with anesthesia by propofol(2.0 mg/kg)only; group B 37 with injection of atropin(0.01 mg/kg)2 min before intravenous propofol; group C 37 cases with injection of fentanyl(1 μg/kg)and propofol; Group D 39 cases with both atropin and fentanyl 2 min before propofol.Operative duration, SP, DP, MAP, HR, SPO 2 and Vt were analyzed. Results In all of the four groups, SP, DP, MAP, HR and Vt fell in different degree after inducing, especially in group A and C at 2 and 4min after inducing(P<0.01).Change scores of injecting pain and operative response in Group A and B were greater than group C and D(P<0.01).A short time drop of SPO 2 and Vt were significant comparing to pre-induction(P<0.01). Conclusions The anesthesia of intravenous allaying propofol with atropin-fentanyl can fulfill the requirement of painless artificial abortion.
出处
《中国妇产科临床杂志》
2003年第5期331-333,共3页
Chinese Journal of Clinical Obstetrics and Gynecology
