摘要
目的探讨海南地区IgA肾病患者临床表现、病理特点及其相关性。方法回顾性总结分析217例经肾活检病理确诊为原发性IgA肾病的临床和病理资料。结果217例IgA肾病患者在30～39岁年龄段发病率最高(50.38%);临床表现以血尿+蛋白尿型最常见(56.68%,123/217),该型病理改变程度较重,Ⅲ级病变以上占38.21%;IgA肾病的病理类型包括了几乎所有原发性肾小球疾病的病理类型,以Ⅰ级病变最为常见(31.34%,68/217),其次为Ⅱ级病变(29.95%,65/217),且随着病理分级程度的进展,临床合并高血压的比例也越高;免疫病理分型中48例为单纯IgA型(22.12%),106例伴补体沉积(48.85%)。结论IgA肾病临床表现多样化,伴高血压患者肾病理改变程度较严重。对无症状血尿伴或不伴蛋白尿患者应尽早行肾活检术,并根据病理类型采用相应的治疗方案。
Objective To study the clinical manifestation,pathological features and their correlation in patients with IgA nephropathy from Hainan Province.Methods The clinical and pathological data of 217 patients with IgA nephropathy diagnosed by renal biopsy were retrospectively analyzed.Results The incidence of IgA nephropathy was the highest in patients at the age of 30-39 years(50.38%).Clinically,IgA nephropathy of hematuria + albuminuria type was the most common among the patients(56.68%,123/217) and associated ...
出处
《南方医科大学学报》
CAS
CSCD
北大核心
2009年第7期1445-1447,共3页
Journal of Southern Medical University
关键词
IGA肾病
临床表现
病理
免疫荧光
电镜
IgA nephropathy/clinical manifestation
IgA nephropathy/pathology
immunofluorescence
electron microscopy
