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The Inhibitory Effects of Rh-endostatin(YH-16) in Combination with Radiotherapy on Lung Adenocarcinoma A549 in Mice and the Underlying Mechanisms 被引量：10

The Inhibitory Effects of Rh-endostatin(YH-16) in Combination with Radiotherapy on Lung Adenocarcinoma A549 in Mice and the Underlying Mechanisms
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摘要 In order to investigate the inhibitory effects of Endostar(rh-endostatin,YH-16)in combination with radiotherapy on lung adenocarcinoma A549 in mice and the interaction mechanisms of combined therapy,the transplantation tumor models of A549 lung adenocarcinoma were established.When the largest diameter of tumor reached 1.0cm,all nude mice were randomly divided into 4 groups:Endostar group,radiotherapy group,radiotherapy plus Endostar(combined treatment)group,and control group(n=6 in each group).The largest d... In order to investigate the inhibitory effects of Endostar(rh-endostatin,YH-16)in combination with radiotherapy on lung adenocarcinoma A549 in mice and the interaction mechanisms of combined therapy,the transplantation tumor models of A549 lung adenocarcinoma were established.When the largest diameter of tumor reached 1.0cm,all nude mice were randomly divided into 4 groups:Endostar group,radiotherapy group,radiotherapy plus Endostar(combined treatment)group,and control group(n=6 in each group).The largest d...
作者 吴辉塔 邓洁 于世英 王馨 陈元
机构地区 Department of Oncology Cancer Center
出处 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2010年第1期108-112,共5页 华中科技大学学报（医学英德文版）
关键词 lung neoplasms human lung adenocarcinoma cell line A549 xenografted tumor recombinant human Endostatin RADIOTHERAPY lung neoplasms human lung adenocarcinoma cell line A549 xenografted tumor recombinant human Endostatin radiotherapy
分类号 R734.2 [医药卫生—肿瘤]
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参考文献10

  • 1Ling Y,,Yang Y,Lu N,et al.Endostar,a novel recombinant human endostatin,exerts antiangiogenic effect via blocking VEGF-induced tyrosine phosphorylation of KDR/Flk-1 of endothelial cells[].Biochemical and Biophysical Research Communications.2007
  • 2Tyldesley S,Boyd C,Schulze K,et al.Estimating the need for radiotherapy for lung cancer: an evidence-based, epidemiologic approach[].International Journal of Radiation Oncology Biology Physics.2001
  • 3Ziche M,Parenti A,Ledda F,et al.Nitric oxide promotes proliferation and plasminogen activator production by coronary venular endothelium through endogenous bFGF[].Circulation Research.1997
  • 4O’ Reilly M S,Boehm T,Shing Y,et al.Endostatin: an endogenous inhibitor of angiogensis and tumor growth[].Cell.1997
  • 5Lee CG,Heijn M,di Tomaso E,et al.Anti-vascular endothelial growth factor treatment augments tumor radiation response under normoxic or hypoxic conditions[].Cancer Research.2000
  • 6Jain PK.Determinants of tumor blood flow: a review[].Cancer Research.1988
  • 7Jain RK.Transport of molecules, particles, and cells in solid tumors[].Annual Review of Biomedical Engineering.1999
  • 8Jain RK.Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy[].Nature Medicine.2001
  • 9Zachary I.Vascular endothelial growth factor[].International J of Bioch & Cell Biol.1998
  • 10Mauceri H J,Hanna N N,Beckett M A,et al.Combined effects of angiostatin and ionizing radiation in antitumour therapy[].Nature.1998

同被引文献41

引证文献10

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Journal of Huazhong University of Science and Technology(Medical Sciences)
2010年 第1期

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