T细胞免疫球蛋白黏蛋白分子3及其配体在慢性病毒感染中的作用研究进展
摘要
病毒感染后的清除主要依赖于细胞免疫和体液免疫组成的免疫反应,其中,病毒特异性CD8+T细胞是主要的效应细胞。在急性病毒感染中,特异性CD8+T细胞通过杀伤病毒感染的细胞,分泌抗病毒细胞因子从而有效清除病毒;
出处
《中华临床医师杂志（电子版）》
CAS
2011年第8期2347-2349,共3页
Chinese Journal of Clinicians(Electronic Edition)
参考文献21
-
1Ying Ju,Nan Hou,Xiaoning Zhang,Di Zhao,Ying Liu,Jinjin Wang,Fang Luan,Wei Shi,Faliang Zhu,Wensheng Sun,Lining Zhang,Chengjiang Gao,Lifen Gao,Xiaohong Liang,Chunhong Ma.Blockade of Tim-3 Pathway Ameliorates Interferon-γ Production from Hepatic CD8^+ T Cells in a Mouse Model of Hepatitis B Virus Infection[J].Cellular & Molecular Immunology,2009,6(1):35-43. 被引量：19
-
2Jennifer J. McIntire,Dale T. Umetsu,Rosemarie H. DeKruyff.TIM-1, a novel allergy and asthma susceptibility gene[J]. Springer Seminars in Immunopathology . 2004 (3-4)
-
3McIntire J J,Umetsu S E,Akbari O,et al.Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nature Immunology . 2001
-
4Monney L,Sabatos CA,Gaglia JL,et al.Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature . 2002
-
5Sabatos CA,Chakravarti S,Cha E,et al.Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nature Immunology . 2003
-
6Sanchez-Fueyo A,Tian J,Picarella D,et al.Tim-3 inhibits T helpertype 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nature Immunology . 2003
-
7Zhu C,Anderson A C,Schubart A,et al.The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nature Immunology . 2005
-
8Kuchroo VK,Umetsu DT,DeKruyff RH,et al.The TIM gene family: emerging roles in immunity and disease. Nature Reviews Immunology . 2003
-
9Ying Ju,Nan Hou,Jing Meng, et al.T cell immunoglobulin-and mucin-domain-containing molecule-3 (Tim-3) Mediates Natural Killer Cell Suppression in Chronic Hepatitis B. Journal of Hepatology . 2010
-
10Golden-Mason L,PalmerBE,KassamN,et al.Negative immune regulatorTim-3is overexpressed on Tcells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+and CD8+TCells. Journal of Virology . 2009
二级参考文献10
-
1Jones RB,Ndhlovu LC,Barbour JD, et al.Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection[].The Journal of Experimental Medicine.2008
-
2Anderson DE.TIM-3 as a therapeutic target in human inflam- matory diseases[].Expert Opinion on Therapeutic Patents.2007
-
3Wang Y,Meng J,Wang X, et al.Expression of human TIM-1 and TIM-3 on lymphocytes from systemic lupus erythematosus patients[].Scandinavian Journal of Immunology.2008
-
4Wada J,Kanwar YS.Identification and characterization of galectin-9, a novel β-galactoside-binding mammalian lectin[].Journal of Biological Chemistry.1997
-
5Monney L,Sabatos CA,Gaglia JL,et al.Th1-specific cell surface protein Ti m-3regulates macrophage activation and severity of an autoi mmune disease[].Nature.2002
-
6Sabatos CA,Chakravarti S,Cha E,et al.Interaction of Ti m-3and Ti m-3ligand regulates T helper type1responses and induction of peripheral tolerance[].Nature Immunology.2003
-
7Sanchez-Fueyo A,Tian J,Picarella D, et al.Tim-3 inhibits T helper type 1-mediated auto-and alloimmune responses and promotes immunological tolerance[].Nature Immunology.2003
-
8Zhu C,Anderson AC,Schubart A,et al.The Ti m-3ligand galectin-9negatively regulates T helper type1i mmunity[].Nature Immunology.2005
-
9Anderson A C,Anderson D E,Bregoli L,et al.Promotion oftissue inflammation by the immune receptor Tim-3 expressedon innate immune cells[].Science.2007
-
10Oikawa T,Kamimura Y,Akiba H,et al.Preferential involve-ment of Tim-3 in the regulation of hepatic CD8+T cells in mu-rine acute graft-versus-host disease[].J Immunol.2006
共引文献18
-
1马德强,郝友华,杨东亮.TIM-3分子与临床疾病相关研究进展[J].免疫学杂志,2010,26(11):996-999. 被引量：2
-
2孟静,刘晓立,郭春,马春红.小鼠Tim-3真核表达载体pTARGET-Tim-3的构建[J].山东大学学报（医学版）,2010,48(11):37-40.
-
3马德强,郝友华,刘敏,徐春利,郭艳,陈悦,陆孟吉,杨东亮.小鼠TIM-3原核表达载体的建立及多克隆抗体的制备与鉴定[J].中国免疫学杂志,2011,27(2):158-162. 被引量：1
-
4任劲松,潘修成.T细胞免疫球蛋白黏蛋白分子3与慢性病毒感染[J].国际流行病学传染病学杂志,2011,38(1):48-50.
-
5程小星,蒋静.Galectin-9／T细胞免疫球蛋白黏蛋白分子3信号通路在抗感染免疫中的作用[J].国际流行病学传染病学杂志,2011,38(6):407-410. 被引量：1
-
6赵慧,王亮,马秀敏,丁剑冰.Tim-3及其配体Galectin-9与病毒感染的关系[J].基础医学与临床,2012,32(9):1095-1098. 被引量：5
-
7梁艳,王皓,仲人前.T淋巴细胞和NK细胞在慢性乙型肝炎病毒感染中的作用[J].检验医学,2014,29(1):4-9. 被引量：5
-
8昝琰璐,田波.反义RNA寡核苷酸及其与脂质体的复合物对于乙型肝炎病毒的抑制（英文）[J].生物化学与生物物理进展,2014,41(4):362-370.
-
9党旭红,左雅慧,原雅艺,杨彪,王超,刘建功.HAVCR2基因沉默对辐射诱发基因组不稳定肝细胞凋亡及细胞周期的影响[J].中华放射医学与防护杂志,2014,34(7):502-506. 被引量：1
-
10侯春梅,郎小玲,肖燕,郑明克,蒋兴伟,肖鹤,陈国江,王仁喜,冯健男,韩根成,沈倍奋,黎燕.Tim-3抗体的生物学活性及应用研究[J].军事医学,2014,38(8):617-620. 被引量：3
-
1蒋英,冯丽丹.乙型肝炎患者健康教育之初探[J].医学信息（手术学分册）,2007,20(11):1027-1028.
-
2体验全科思维，阅读发现价值[J].中国全科医学（医生读者版）,2012,15(1):46-47.
-
3翟淑萍.治疗婴幼儿上呼吸道感染的良药[J].家庭用药,2005(11):53-53.
-
4曾朦,何平.尘肺病易感基因研究进展[J].新疆医学,2016,46(2):231-232. 被引量：1
-
5刘小花,陈宇宁,陈华根.医务人员HIV职业暴露的危险因素与自我防护进展[J].现代医药卫生,2016,32(18):2830-2833. 被引量：3
-
6杨春梅,刘会敏.脊髓灰质炎后遗症患者血清HBV感染状况调查[J].胃肠病学和肝病学杂志,2005,14(3):286-287.
-
7卢彬彬,董莉.信阳市平桥区中小学生乙肝表面抗原的检测分析[J].职业与健康,2003,19(12):97-98. 被引量：1
-
8李云.家长留意:柯萨奇病毒偏爱儿童[J].健康必读,2003(9):46-47.
-
9王凤.乙肝患者怎样保护家人和朋友[J].祝您健康,2012(9):46-46.
-
10柯江.湛江市大专生乙型肝炎病毒表面抗原调查与相关因素分析[J].卫生职业教育,2005,23(16):101-102.
