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生物大分子结晶技术研究进展 被引量：4

Progress in Research of Technologies for Crystallization of Biological Macromolecules
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摘要 获得具有高分辨率的晶体是目前生物大分子结构测定的主要瓶颈,生物大分子的结晶是一个复杂的物理化学过程,涉及多方面的影响因素。本文综述了近年来生物大分子结晶的热点方法和技术。 Obtaining the high-resolution crystal structure has become a bottleneck for structure determination of biological macromolecules.The crystallization of biological macromolecules is a complicated process influenced by many parameters.The recent technologies for preparing crystal of biological macromolecules as well as techniques for controlling the crystallization process are reviewed.
作者 徐乐慧 洪鸣凰 赵文杰 任国宾
机构地区 中国医药工业研究总院上海医药工业研究院药物晶体工程研究实验室
出处 《中国医药工业杂志》 CAS CSCD 北大核心 2011年第7期554-559,共6页 Chinese Journal of Pharmaceuticals
基金 国家"重大新药创制"科技重大专项资助(2009ZX09301-007)
关键词 生物大分子 结晶 晶体 综述 biological macromolecules crystallization crystal reviews
分类号 TQ46 [化学工程—制药化工]
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参考文献31

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  • 2Hiroshi Y. Yoshikawa,Ryota Murai,Syou Maki,Tomoya Kitatani,Shigeru Sugiyama,Gen Sazaki,Hiroaki Adachi,Tsuyoshi Inoue,Hiroyoshi Matsumura,Kazufumi Takano,Satoshi Murakami,Takatomo Sasaki,Yusuke Mori.Laser energy dependence on femtosecond laser-induced nucleation of protein[J]. Applied Physics A . 2008 (4)
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二级参考文献37

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共引文献9

同被引文献40

引证文献4

二级引证文献1

中国医药工业杂志
2011年 第7期

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